European Heart Journal Advance Access originally published online on November 28, 2006
European Heart Journal 2007 28(5):533-539; doi:10.1093/eurheartj/ehl390
A clinical survival score predicts the likelihood to benefit from preoperative thallium scanning and coronary revascularization before major vascular surgery
1 Departments of Anaesthesiology and Critical Care Medicine, Hebrew University, Hadassah Medical Center, Jerusalem 91120, Israel
2 Cardiology Hebrew University, Hadassah Medical Center, Jerusalem 91120, Israel
3 Vascular Surgery Hebrew University, Hadassah Medical Center, Jerusalem 91120, Israel
4 Nuclear Medicine Hebrew University, Hadassah Medical Center, Jerusalem 91120, Israel
Received 23 June 2006; revised 9 October 2006; accepted 3 November 2006; online publish-ahead-of-print 27 November 2006.
* Corresponding address. Tel: +972-2-6777269; fax: +972-2-6429392. E-mail address: gio{at}cc.huji.ac.il
See page 519 for the editorial comment on this article (doi:10.1093/eurheartj/ehl523)
Aims Guidelines advocate selective non-invasive testing before major non-cardiac surgery, yet data defining who may benefit from such tests is lacking. We aimed to find the predictors that define patients who are most likely to benefit from preoperative cardiac testing and coronary revascularization (CR).
Methods and results In 624 consecutive major vascular surgery patients, the preoperative thallium scanning (PTS) results and subsequent CRs were correlated with long-term (3–15 years) survival. Of all patients, 510 (80.6%) had PTS, 154 (24.7%) had moderate-severe ischaemia on PTS, and 96 (15.4%) underwent CR. Seven predictors: age 
65, diabetes, cerebrovascular disease, ischaemic heart disease, congestive heart failure, ST-depression on preoperative ECG, and renal insufficiency, independently determined long-term survival. A long-term survival score (LTSS) comprised of these predictors, divided all patients into low, intermediate, and high-risk groups (0–1, 2–3, 4 predictors, respectively) with a 5-year survival of 83 ± 2%, 60 ± 3%, and 34 ± 6%, respectively. Compared with low-risk patients, intermediate and high-risk patients had worse survival [HR (CI) = 2.6 (2.0–3.4) and 5.9 (4.1–8.9), respectively, P < 0.001]. Yet, only the intermediate-risk group had better long-term survival following preoperative CR [HR = 0.48 (0.31–0.75), P = 0.001]. The low-risk groups' favourable survival and high-risk groups' poor survival were not significantly affected by CR.
Conclusion Intermediate-risk patients (LTSS 2–3) are most likely to have a long-term survival benefit from PTS and CR.
Key Words: Preoperative thallium scanning • Coronary revascularization • Vascular surgery • Long-term survival
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EHJ 2007 28: 519-521.[Extract] [FREE Full Text]
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