Skip Navigation


European Heart Journal Advance Access originally published online on June 20, 2008
European Heart Journal 2008 29(16):1992-1999; doi:10.1093/eurheartj/ehn267
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
29/16/1992    most recent
ehn267v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Ennezat, P. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ennezat, P. V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

The effect of ageing on cardiac remodelling and hospitalization for heart failure after an inaugural anterior myocardial infarction

Pierre V. Ennezat1, Nicolas Lamblin1, Frédéric Mouquet1, Olivier Tricot2, Philippe Quandalle3, Valérie Aumégeat4, Octave Equine5, Olivier Nugue6, Benoit Segrestin7, Pascal de Groote1, Christophe Bauters1,8,* on behalf of the REVE Investigators

1 Centre Hospitalier Régional et Universitaire de Lille, Lille, France
2 Centre Hospitalier de Dunkerque, Dunkerque, France
3 Centre Hospitalier de Roubaix, Roubaix, France
4 Centre Hospitalier de Lens, Lens, France
5 Centre Hospitalier de Béthune, Béthune, France
6 Centre Hospitalier de Boulogne, Boulogne, France
7 Centre Hospitalier de St Omer, St Omer, France
8 Faculté de Médecine de Lille, Hôpital Cardiologique, CHRU de Lille, Boul. Prof. Leclercq, 59037 Lille Cedex, France

Received 25 November 2007; revised 5 May 2008; accepted 29 May 2008; online publish-ahead-of-print 20 June 2008.

* Corresponding author. Tel: +33 320 445 045, Fax: +33 320 444 881, Email: cbauters{at}chru-lille.fr

Aims: Following myocardial infarction (MI), both age and left ventricular (LV) remodelling are associated with an increased risk of adverse events. We tested the hypothesis that the increased incidence of heart failure following MI in elderly patients is associated with a greater propensity for LV remodelling.

Methods and results: We monitored 266 patients with anterior MI. Echocardiographic studies were performed at hospital discharge, at 3 months, and at 1 year following hospitalization for MI. A clinical follow-up examination was performed after 3 years. Left ventricular remodelling was documented by an increase in LV end-diastolic volume after 1 year. Left ventricular end-diastolic and end-systolic volumes did not differ with age for all time points studied. Left ventricular remodelling was observed in 31, 26, 34, and 34% of patients <48, 48–57, 58–71, and >71 years of age, respectively. The 3 year heart-failure hospitalization rates were 1.9, 1.5, 11.0, and 20.3% for patients <48, 48–57, 58–71, and >71 years of age, respectively. Hospitalization for heart failure was more frequent in older patients.

Conclusion: We found that age was a major determinant of subsequent re-hospitalization for heart failure. However, we found no significant association between age and the LV remodelling process.

Key Words: Myocardial infarction • Ageing • Heart failure • Ventricular remodelling


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.