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European Heart Journal 1983 4(9):662-667;
Copyright © 1983 by the European Society of Cardiology.
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© 1983, by the European Society of Cardiology

Interpretation of the effects of propranolol on coronary reactive hyperaemia

M. THOMAS, I. GABE and C. MILLS

The Midhurst Medical Research Institute Midhurst, West Sussex, U.K.

Received 30 June 1982; revised 12 November 1982; .

Address for reprints: Dr Michael Thomas, The Midhurst Medical Research Institute, Midhurst, West Sussex GU29 0BL, U.K.

Abstract

The effect of propranolol on the hyperaemic response after transient coronary arterial occlusion has been evaluated. The excess volume of blood delivered to the myocardium after an occlusion is diminished after propranolol in proportion to the reduced coronary blood flow. From the findings it is not necessary to postulate a change in the intrinsic mechanisms of reactive hyperaemia after propranolol has been given.

Key Words: Propranolol • reactive hyperaemia • coronary vasoconstriction


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