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European Heart Journal 1984 5(1):35-42;
Copyright © 1984 by the European Society of Cardiology.
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© 1984 The European Society of Cardiology

Survival in 1041 patients with consecutive aorto-coronary bypass operations

K. LAIRD-MEETER, O.C.K.M. PENN, M.M.P. HAALEBOS, R. van DOMBURG, J. LUBSEN, E. BOS and P.G. HUGENHOLTZ

Thoraxcenter, University Hospital Dijkzigt, and Erasmus University Rotterdam The Netherlands

Received 12 April 1983; .

Requests for reprints to: Karin Laird-Meeter MD, Thoraxcenter, Erasmus University, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

Abstract

The first 1041 patients who underwent an isolated aorto-coronary bypass operation in the same institution since it opened in 1971, were followed for up to 10 years to determine their prognosis. The mean follow- up time was 3-5 years. The probability of survival at five years was 94 ±2% (95% confidence limits). This was similar to the survival of the general Dutch population matched for age and sex.Multivariate survival analysis with the proportional hazards model did reveal a relationship of the rate of death with sex and age at operation; however this was not significant. There was a trend to a higher death rate with more vascular involvement (rate ratio of 3 vessel-versus 1 vessel disease of 1-9, N.S.) and a significant association with a low ejection fraction (EF) (ratio EF≤)0.30 v. EF ≥0.55 of 2.7. P<0.05).Though surgery seems to eradicate the poor longterm outlook for patients with more serious vascular disease, the adverse influence of decreased left ventricular function on survival is not changed.

Key Words: Aorto-coronary bypass surgery • survival • coronary artery disease • left ventricular function


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