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European Heart Journal 1984 5(12):1010-1012;
Copyright © 1984 by the European Society of Cardiology.
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© 1984 The European Society of Cardiology

Serum sickness complicating intravenous streptokinase therapy in acute myocardial infarction

D. ALEXOPOULOS, A. E. G. RAINE and S. M. COBBE

Cardiac Department, John Radcliffe Hospital Oxford U.K.

Received 15 May 1984; revised 8 October 1984; .

Address for Correspondence: Dr S. M. Cobbe, Cardiac Department. John Radeliffe Hospital, Oxford OX3 9DU, U K.

Abstract

A case of delayed serum sickness with transient renal impairment is described in a patient who received early high dose intravenous streptokinase following acute myocardial infarction. Review of the literature suggests that serum sickness after streptokinase may occur independently of the dose or route of administration, and could potentially complicate intracoronary streptokinase therapy.

Key Words: Serum sickness • streptokinase • myocardial infarction


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