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European Heart Journal 1984 5(4):304-307;
Copyright © 1984 by the European Society of Cardiology.
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© 1984 The European Society of Cardiology

Nonparoxysmal atrioventricular junctional rhythm. A clinical and electrophysiologic study

V. SANTINELLI, M. CHIARIELLO and M. CONDORELLI

Istituto di Clinica Medica I, Università di Napoli 80131 Napoli, Italy

Received 14 September 1983; revised 2 December 1983; .

Request for reprints to. Vincenzo Santinelli, M.D., Istituto di Clinica Medica I, Universiti di Napoli, Via S. Pansini, 5, 80131, Napoli, Italy.

Abstract

The patient, a 74-year-old man, developed a persistent nonparoxysmal junctional accelerated rhythm at rate of 60-75 beats min–1 because of chronic depressed sinus node function. Intravenous atropine resulted in no change of junctional pacemaker rate but i.v. isoproterenol significantly accelerated it suggesting that autonomic neural imbalance might underlie the mechanism of nonparoxysmal junctional rhythm. Intravenous verapamil (10 mg) induced no change in the junctional pacemaker rate and postpacing pauses suggesting that the slow inward current did not play an important role in the nonparoxysmal junctional rhythm.

Key Words: Nonparoxysmal AV junctional rhythm • automaticity • verapamil


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