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European Heart Journal 1984 5(5):348-353;
Copyright © 1984 by the European Society of Cardiology.
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© 1984 The European Society of Cardiology

Do beta blockers prevent pressor responses to mental stress and physical exercise?

B. FRANÇOIS, R. CAHEN, M.F. GRAVEJAT and M. ESTRADE

Division of Nephrology and Alexis Carrel School of Medicine, Centre Hospitalier Lyon Sud France

Received 10 June 1983; revised 9 December 1983; .

Requests for reprints to: Prof. B. Francois, Alexis Carrel School of Medicine, Claude Bernard University, Division ofNephrology, Centre Hospitalier Lyon Sud 69310 Pierre-Benite. France.

Abstract

Do beta blockers prevent the elevation of blood pressure induced by physical exercise and mental stress= The variations of blood pressure and pulse rate observed with dynamic effort and during tests of mental calculation, colour stress, and grip strength were measured in 15 hypertensive patients, before and after treatment with alenolol (100 mg day–1) and in a series of 16 normolensive control subjects.

With treatment, the systolic and diastolic blood pressures and the pulse rate were significantly lowered in the hypertensive patients at rest. The tests of mental stress and static physical effort caused a rise in blood pressure, significantly greater in the untreated patients than in the control subjects. Atenolol diminished the rise in systolic blood pressure and pulse rate secondary to a dynamic effort, but did not significantly alter the blood pressure variations induced by static physical effort and mental stress. These findings are in agreement with previous results obtained with other beta blockers.

Key Words: Blood pressure • beta adrenergic blocking agents • colour stress • mathematical tests • dynamic exercise • isometric exertion


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