Skip Navigation

European Heart Journal 1984 5(8):617-621;
Copyright © 1984 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by SCHOFER, J.
Right arrow Articles by MATHEY, D. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SCHOFER, J.
Right arrow Articles by MATHEY, D. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1984 The European Society of Cardiology

Assessment of myocardial necrosis immediately after intracoronary thrombolysis by intracoronary injection of technetium-99m pyrophosphate

J. SCHOFER, P. STRITZKE*, R. MONTZ* and D. G. MATHEY

Department of Cardiology
*Department of Nuclear Medicine, University Hospital Eppendorf Hamburg, F.R.G.

Received 5 September 1983; revised 10 May 1984; .

Address for correspondence: D. G. Mathey, M.D., Dept. of Cardiology, Univ Hospital Eppendorf, Martinistr. 52,2000 Hamburg 20, F.R.G.

Abstract

To assess myocardial necrosis immediately after intracoronary thrombolysis, thallium-201 (TL-201) and technetium-99m pyrophosphate (Tc-99m PYP) were injected simultaneously into the coronary artery in 25 patients with acute transmural myocardial infarction. In 17 of the 25 patients, the occluded coronary artery was reopened. Minutes after the intracoronary injection of Tc-99m PYP into the reopened coronary artery a localized accumulation was seen within the area of the Tl-201 defect in all patients. Control intravenous scintigraphy, which was performed in 8 of these 17 patients 1–6 days later, and in 2 patients 18 and 42 days after infarction, revealed a Tc- 99m PYP spot similar to that of the acute intracoronary Tc-99m PYP scintigram in all 10 patients.

In the 8 of the 25 patients, in whom intracoronary thrombolysis failed, no localized Tc-99m PYP accumulation was seen after injection into the infarct vessel. In 5 of these patients, a control intravenous scintigram, performed 1–8 days later, resulted in a Tc-99m PYP spot in the area of the Tl-201 defect.

We conclude that, in the presence of therapeutic or spontaneous reperfusion, Tc-99m PYP scintigraphy may provide a useful method of assessing myocardial necrosis during the early stage of an acute myocardial infarction.

Key Words: Acute myocardial infarction • intracoronary thrombolysis • intracoronary technetium-99m pyrophosphate scintigraphy


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.