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European Heart Journal 1985 6(6):490-496;
Copyright © 1985 by the European Society of Cardiology.
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© 1985 The European Society of Cardiology

Role of blood pressure response to provocative tests in the prediction of hypertension inadolescents

M. RADICE, C. ALLI, F. AVANZINI, M. DI TULLIO, G. MARIOTTI, E. TAIOLI, A. ZUSSINO and G. FOLLI

Clinica Medica VI, Universita di Milano Milano, Italy

Received 25 October 1984; revised 5 March 1985; .

Dr Maria Radice, via Muratori 29, 20135 Milano, Italy.

Abstract

To assess the value of exercise stress testing and of mental stress as predictors of hypertension, we studied 130 normotensive males 14–18 years of age. Sixty-five had at least one hypertensive parent (SHT), while 65 had normotensive parents (SNT). Systolic (SBP) and diastolic (DBP) blood pressure, rate-pressure product (RPP) and 12-lead ECG were recorded at rest, throughout the tests and during the recovery phase.The two groups were not significantly different at rest for the examined variables. However, the SHT group showed a greater average SBP than the SNT group (198.4±18.7 vs 189.5±14.9 mmHg; P<0.05) at the peak of exercise. A significantly higher proportion of SHT subjects (40.0% vs 18.5%: P<0.01) had SBP >200 mmHg. No difference in the ECG pattern between the two groups was observed.During mental stress, no significant differences in the examined variables between the two groups were noted, although SBP, DBP, HR and RPP were slightly higher in SHT than in SNT subjects.These data suggest that the SBP response to dynamic exercise may be a good predictor of hypertension in subjects at risk.

Key Words: blood pressure • genetic risk for hypertension • dynamic exercise • mental stress


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