Skip Navigation

European Heart Journal 1987 8(4):395-401;
Copyright © 1987 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by FINDLAY, I. N.
Right arrow Articles by DARGIE, H. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FINDLAY, I. N.
Right arrow Articles by DARGIE, H. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1987 The European Society of Cardiology

Gold 195m in the assessment of the cold pressor test by first pass radionuclide ventriculography

I. N. FINDLAY, J. T. WILSON, E. HENDERSON, G. GILLEN, A. T. ELLIOTT and H. J. DARGIE

Department of Cardiology, Western Infirmary Glasgow G11 6NT, U.K.

Received 27 June 1986; revised 22 September 1986; .

Dr Iain N Findlay, Department of Cardiology, Western Infirmary, Glasgow G11 6NT, U.K

Abstract

First pass radionuclide ventriculography was performed with gold 195m in a sequential evaluation of left ventricular ejection fraction during cold pressor stimulation. We studied 10 normal controls, 10 patients with angina pectoris who had proven coronary artery disease and normal left ventricular function during contrast angiography and 10 patients with dilated cardiomyopathy with normal coronary arteries and impaired left ventricular function at contrast angiography.

Mean resting ejection fraction was similar in controls and patients with coronary heart disease (57 ± 2 vs 58 ± 3) but was significantly lower in the cardiomyopathic subjects (27 ± 4, P < 0.001). After 30 seconds cold pressor stimulation, mean left ventricular ejection fraction fell in the normal controls (57 ± 2 to 52 ± 2, P <0.05) but was unchanged in those with coronary heart disease and dilated cardiomyopathy (58 ± 3 to 55 ± 3 and 27 ± 4 to 24 ± 4, both NS). No further significant change occurred after 2.5 minutes stimulation (53 ± 1, 58 ± 3 and 23 ± 3, respectively). There was no difference in the pattern of left ventricular ejection fraction response between the groups. Six controls, 4 patients with coronary heart disease and 4 patients with dilated cardiomyopathy had a significant fall in left ventricular ejection fraction and 4, 5 and 6, respectively, developed a new or further deterioration in regional wall motion. Thus neither changes in regional wall motion nor left ventricular ejection fraction response distinguished either patient group from the normal controls. We do not recommend cold pressor stimulation as a diagnostic test for coronary heart disease.

Key Words: Cold pressor test • Gold 195m first pass radionuclide ventriculography


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.