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European Heart Journal 1987 8(8):840-844;
Copyright © 1987 by the European Society of Cardiology.
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© 1987 The European Society of Cardiology

Role of QT prolongation secondary to a postextrasystolic pause as a possible mechanism for the induction of ventricular fibrillation. Report of two cases

M. DI BIASE, S. FAVALE, U. RIZZO, F. MINAFRA and P. RIZZON

Division of Cardiology, University of Bari Bari, Italy

Received 4 August 1986; revised 2 December 1986; .

Dr Matteo Di Biase, Clinica Medica I, Cardiologia, Policlinico 70124 Bari, ItaLY

Two patients developed ventricular fibrillation (VF) while undergoing continuous electrocardiographic monitoring. Analysis showed that VF appeared only when a particular combination of circumstances occurred: a postextrasystolic pause. QT prolongation of the subsequent beat and a premature ventricular beat that did not have a short coupling interval. The relevance of this sequence as a trigger mechanism of VF is discussed.

Key Words: Holter monitoring; • postextrasystolic pause; • QT prolongation; • ventricular fibrillation.


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