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European Heart Journal 1987 8(8):895-901;
Copyright © 1987 by the European Society of Cardiology.
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© 1987 The European Society of Cardiology

Inappropriate left ventricular hypertrophy in minor aortic valve disease: a source of error in clinical assessment

T. CRIPPS, G. LEECH and A. LEATHAM

Department of Cardiological Sciences, St George's Hospital Blackshaw Road, London SW170QT, U.K.

Received 24 November 1986; revised 21 January 1987; .

Dr T. Cripps, Department of Cardiological Sciences, St Georges Hospital, Blackshaw Road, London SW170QT, U.K.

A group of patients with minor aortic valve disease and inappropriately severe left ventricular hypertrophy is described. Clinical, electrocardiographic and echocardiographic assessment of the degree of left ventricular hypertrophy suggested that they had haemodynamically severe aortic stenosis but this was not borne out at cardiac catheterisation. Although a chance association between non-obstructive hypertrophic cardiomyopathy and mild aortic stenosis may have been responsible, an abnormally severe hypertrophic response to minor aortic outflow obstruction is proposed as another possible explanation. The association between minor aortic valve disease and severe left ventricular hypertrophy should be considered when assessing aortic stenosis since the prognosis with medical management seems good and valve replacement is likely to be of no benefit in such cases.

Key Words: Aortic valve disease, • left ventricular hypertrophy.


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