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European Heart Journal 1987 8(8):910-911;
Copyright © 1987 by the European Society of Cardiology.
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© 1987 The European Society of Cardiology

Rapid relief of spontaneous angina by intraventricular diltiazem: Systemic and regional coronary haemodynamic determinants

C. VIGORITO, A. GIORDANO, N. MAUREA, B. TUCCILLO and F. RENGO

1 Cattedra di Medicina Interna, Istituto di Medicina Interna, Cardiologia e Chirurgia Cardiovascolare, University of Naples, II School of Medicine Naples, Italy

Received 15 May 1986; revised 22 December 1986; .

Carlo Vigorito, MD. I Cattedra di Medicina Interna, Istituto di Medicina Interna, Cardiologia e Chirurgia Cardiovascolare, II Facolta' di Medicina e Chirurgia, Universita' di Napoli, Via S. Pansini, 5, 80131, Napoli, Italy.

The authors describe a case of spontaneous angina during catheterization in a patient with left anterior descending and circumflex stenosis promptly relieved by diltiazem, 10 mg, given in the left ventricle. Coronary and systemic haemodynamics measured during and at the end of angina demonstrated an increase in blood flow to the ischaemic myocardium as the mechanism responsible for the diltiazem-induced angina relief.

Key Words: Spontaneous angina, • diltiazem, • coronary haemodynamics.


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