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European Heart Journal 1988 9(10):1074-1080;
Copyright © 1988 by the European Society of Cardiology.
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© 1988 The European Society of Cardiology

Effects of cold on ST amplitudes and blood pressure during exercise in angina pectoris

A. ROSENGREN*, B. WENNERBLOM{dagger}, T. BJURÖ, L. WILHELMSEN* and B. BAKE{ddagger},

*Department of Medicine, Östra sjukhuset Göteborg, Sweden
{dagger}Department of Medicine 1, Sahlgrenksa sjukhuset Göteborg, Sweden
{dagger}Department of Clinical Physiology, Sahlgrenska sjukhuset Göteborg, Sweden

Received 23 June 1987; revised 8 April 1988; .

Address for correspondence: Björn Bake, Department of Clinical Physiology, Sahlgrenska sjukhuset, S-41345 Göteborg, Sweden.

Abstract

To investigate the mechanisms of cold susceptibility in angina pectoris nine male angina patients were studied. All were cold susceptible by history and had developed ischaemic ST changes during a previous exercise test. The patients underwent two additional bicycle exercise tests, one in a cold chamber with an average temperature of –8°C, and the other at room temperature. The ECG was computer analysed and the intra-arterial blood pressure was measured. No significant decrease in work capacity was found during exercise in the cold chamber. In the cold, systolic blood pressure was consistently higher throughout the test and in seven of nine subjects ST depression was more pronounced at corresponding workloads. ST depression was also analysed versus heart work which was assessed as rate pressure product. In the cold, 1 mm ST depression appeared at a somewhat higher rate pressure product when compared to room temperature. It was concluded, therefore, that an augmented heart work, secondary to substantial increases in blood pressure, appears to account for the cold-induced increase in ST depression found in the angina patients in this study.

Key Words: Angina pectoris • cold • exercise testing • arterial blood pressure • ST amplitude


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