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European Heart Journal 1988 9(10):1155-1157;
Copyright © 1988 by the European Society of Cardiology.
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© 1988 The European Society of Cardiology

Prinzmetal's angina during cyclophosphamide therapy

T. STEFENELLI, C. C. ZIELINSKI, H. MAYR and W. SCOHEITHAUER

Departments of Cardiology, Medicine II, and Gastroenterology and Hepatology II, University of Vienna Vienna, Austria

Received 15 April 1988; revised 6 June 1988; .

Address for reprints: Harald Mayr, M.D., Department of Cardiology, University of Vienna, A-1090 Wien, Garnisongasse 13, Austria.

Abstract

The first case of cyclophosphamide-induced myocardial ischaemia with electrocardiographically documented ST-segment elevation, T-wave inversion, arrhythmias, angina pectoris and cardiac decompensation is reported. The data suggest that cyclophosphamides induces myocardial ischaemia by eliciting coronary artery spasm.

Key Words: cyclophosphamide • Prinzmetal angina • cardiotoxicity


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