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European Heart Journal 1988 9(3):238-242;
Copyright © 1988 by the European Society of Cardiology.
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© 1988 The European Society of Cardiology

The Belgian Heart Disease Prevention Project: 10-Year mortality follow-up

G. DE BACKER*, M. KORNITZER{dagger}, M. DRAMAIX{dagger}, F. KITTEL{dagger}, C. TIOLLY{dagger}, M. GRAFFAR{dagger} and K. VUYLSTEEK*

*Dienst voor Hygiëne en Sociale Geneeskunde Rijksuniversiteit Gent, Belgium
{dagger}Laboratoire d'Epidémiologie et de Medecine Sociale, Universite Libre de Bruxelles Belgium

Received 15 May 1987; revised 12 August 1987; .

Abstract

The Belgian Heart Disease Prevention Project was a controlled, randomized multifactorial intervention trial in middle-aged men which lasted 6 years. Significant net differences between intervention and control groups were observed in change in risk profile, in total mortality and in CHD incidence. The net difference in risk profile change was greatest at two years, intermediate at four years and minimal at six years. Total and cause-specific mortality rates were systematically followed from the 6th to the 10th year. Follow-up at 10 years was 99.3% complete. The differences between intervention and control groups in total, coronary and cardiovascular mortality reduced from the 6th to the 10th year. The results suggest that changes in risk profile are rapidly followed by changes in cardiovascular mortality, but this applies in both directions. Thus risk reduction should be maintained in order to achieve a long-lasting preventive effect.

Key Words: Preventive cardiology • epidemiology • coronary heart disease


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