Copyright © 1988 by the European Society of Cardiology.
© 1988 The European Society of Cardiology
Myocardial infarction in patients with diabetes mellitus
Department of Cardiology, Kärnsjukhuset S-541 85 Skövde, Sweden
Received 28 May 1987; revised 2 September 1987; .
Abstract
The occurrence of diabetes mellitus and its complications and prognosis in an unselected consecutive series of patients with myocardial infarction (MI) was studied. Out of 341 patients 81 (24%) haddiabetes. Comparisons were made between patients with and without diabetes. Age was higher and female sex more common among patients with diabetes. A considerable proportion of patients with diabetes were on digitalis when admitted (51%) compared to 20% of those without. Ventricular tachy arrhythmias requiring treatment did not differ between the two groups. High-degree A V-block was considerably more common among patients with diabetes (19%) than those without (7% P<0.001). Mortality was higher in diabetic than in non-diabetic patients both during the hospital phase (25%, vs. 16% P < 002) and during one year of follow-up (53% vs. 28% P < 0.001). Diabetes was an independent prognostic risk factor for death (P< 001). Fatal reinfarction was more common among diabetic patients (30%) than those without (14%; P<0.05). In conclusion diabetics with MI have a poor prognosis despite improvements in coronary care. The high late mortality is to a large extent related to a high proportion of fatal reinfarctions.
Key Words: Diabetes myocardial infarction prognosis mortality complications
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
O. E. Okosieme, R. Peter, M. Usman, H. Bolusani, P. Suruliram, L. George, and L. M. Evans Can Admission and Fasting Glucose Reliably Identify Undiagnosed Diabetes in Patients With Acute Coronary Syndrome? Diabetes Care, October 1, 2008; 31(10): 1955 - 1959. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Norhammar, J. Lindback, L. Ryden, L. Wallentin, U. Stenestrand, and on behalf of the Register of Information and Knowl Improved but still high short- and long-term mortality rates after myocardial infarction in patients with diabetes mellitus: a time-trend report from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admission Heart, December 1, 2007; 93(12): 1577 - 1583. [Abstract] [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, L. Ryden, E. Standl, M. Bartnik, G. V. d. Berghe, J. Betteridge, M.-J. de Boer, F. Cosentino, B. Jonsson, M. Laakso, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: full text: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) Eur. Heart J. Suppl., June 1, 2007; 9(suppl_C): C3 - C74. [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, L. Ryden, E. Standl, M. Bartnik, G. Van den Berghe, J. Betteridge, M.-J. de Boer, F. Cosentino, B. Jonsson, M. Laakso, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) Eur. Heart J., January 1, 2007; 28(1): 88 - 136. [Full Text] [PDF] |
||||
![]() |
C. P Gale, C. Kashinath, and P. Brooksby The association between hyperglycaemia and elevated troponin levels on mortality in acute coronary syndromes Diabetes and Vascular Disease Research, September 1, 2006; 3(2): 80 - 83. [Abstract] [PDF] |
||||
![]() |
N. W. Cheung, V. W. Wong, and M. McLean The Hyperglycemia: Intensive Insulin Infusion In Infarction (HI-5) Study: A randomized controlled trial of insulin infusion therapy for myocardial infarction Diabetes Care, April 1, 2006; 29(4): 765 - 770. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. M. Murcia, C. H. Hennekens, G. A. Lamas, M. Jimenez-Navarro, J. L. Rouleau, G. C. Flaker, S. Goldman, H. Skali, E. Braunwald, and M. A. Pfeffer Impact of Diabetes on Mortality in Patients With Myocardial Infarction and Left Ventricular Dysfunction Arch Intern Med, November 8, 2004; 164(20): 2273 - 2279. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Stranders, M. Diamant, R. E. van Gelder, H. J. Spruijt, J. W. R. Twisk, R. J. Heine, and F. C. Visser Admission Blood Glucose Level as Risk Indicator of Death After Myocardial Infarction in Patients With and Without Diabetes Mellitus Arch Intern Med, May 10, 2004; 164(9): 982 - 988. [Abstract] [Full Text] [PDF] |
||||
![]() |
P L Sanchez, J L Morinigo, P Pabon, F Martin, I Piedra, I F Palacios, and C Martin-Luengo Prognostic relations between inflammatory markers and mortality in diabetic patients with non-ST elevation acute coronary syndrome Heart, March 1, 2004; 90(3): 264 - 269. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Norhammar, K. Malmberg, E. Diderholm, B. Lagerqvist, B. Lindahl, L. Ryden, and L. Wallentin Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularization J. Am. Coll. Cardiol., February 18, 2004; 43(4): 585 - 591. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Zeller, Y. Cottin, M.-C. Brindisi, G. Dentan, Y. Laurent, L. Janin-Manificat, I. L'Huillier, J.-C. Beer, C. Touzery, H. Makki, et al. Impaired fasting glucose and cardiogenic shock in patients with acute myocardial infarction Eur. Heart J., February 2, 2004; 25(4): 308 - 312. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Tenerz, A. Norhammar, A. Silveira, A. Hamsten, G. Nilsson, L. Ryden, and K. Malmberg Diabetes, Insulin Resistance, and the Metabolic Syndrome in Patients With Acute Myocardial Infarction Without Previously Known Diabetes Diabetes Care, October 1, 2003; 26(10): 2770 - 2776. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Tikiz, U. Tezcan, M. Ileri, Y. Balbay, R. Atak, and E. Kutuk Diabetes Mellitus Adversely Affects the Outcomes of Thrombolytic Therapy in Patients with Acute Myocardial Infarction Angiology, July 1, 2003; 54(4): 449 - 456. [Abstract] [PDF] |
||||
![]() |
A. Norhammar, K. Malmberg, L. Ryden, P. Tornvall, U. Stenestrand, L. Wallentin, and For the Register of Information and Knowledge abou Under utilisation of evidence-based treatment partial explanation for the unfavourable prognosis in diabetic patients with acute myocardial infarction Eur. Heart J., May 1, 2003; 24(9): 838 - 844. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. R. Niefeld, J. B. Braunstein, A. W. Wu, C. D. Saudek, W. E. Weller, and G. F. Anderson Preventable Hospitalization Among Elderly Medicare Beneficiaries With Type 2 Diabetes Diabetes Care, May 1, 2003; 26(5): 1344 - 1349. [Abstract] [Full Text] [PDF] |
||||
![]() |
J Herlitz, A Bang, J Gunnarsson, J Engdahl, B W Karlson, J Lindqvist, and L Waagstein Factors associated with survival to hospital discharge among patients hospitalised alive after out of hospital cardiac arrest: change in outcome over 20 years in the community of Goteborg, Sweden Heart, January 1, 2003; 89(1): 25 - 30. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. M. Chow, C. C. Szeto, T. Y.-h. Wong, F. K.-t. Leung, A. Cheuk, and P. K.-t. Li Diabetic Muscle Infarction: Myocardial infarct equivalent Diabetes Care, October 1, 2002; 25(10): 1895 - 1895. [Full Text] |
||||
![]() |
J Sala, R Masia, F-J Gonzalez de Molina, J M Fernandez-Real, M Gil, D Bosch, W Ricart, M Senti, and J Marrugat Short-term mortality of myocardial infarction patients with diabetes or hyperglycaemia during admission J Epidemiol Community Health, September 1, 2002; 56(9): 707 - 712. [Abstract] [Full Text] [PDF] |
||||
![]() |
A Tenerz, I Lonnberg, C Berne, G Nilsson, and J Leppert Myocardial infarction and prevalence of diabetes mellitus. Is increased casual blood glucose at admission a reliable criterion for the diagnosis of diabetes? Eur. Heart J., July 1, 2001; 22(13): 1102 - 1110. [Abstract] [PDF] |
||||
![]() |
J. R. Kersten, M. W. Montgomery, T. Ghassemi, E. R. Gross, W. G. Toller, P. S. Pagel, and D. C. Warltier Diabetes and hyperglycemia impair activation of mitochondrial KATP channels Am J Physiol Heart Circ Physiol, April 1, 2001; 280(4): H1744 - H1750. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Melchior, C. Rask-Madsen, C. Torp-Pedersen, P. Hildebrandt, L. Kober, and G. Jensen The impact of heart failure on prognosis of diabetic and non-diabetic patients with myocardial infarction: a 15-year follow-up study Eur J Heart Fail, January 1, 2001; 3(1): 83 - 90. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. M. Detre, M. S. Lombardero, M. M. Brooks, R. M. Hardison, R. Holubkov, G. Sopko, R. L. Frye, B. R. Chaitman, and The Bypass Angioplasty Revascularization Investiga The Effect of Previous Coronary-Artery Bypass Surgery on the Prognosis of Patients with Diabetes Who Have Acute Myocardial Infarction N. Engl. J. Med., April 6, 2000; 342(14): 989 - 997. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. R. Kersten and D. C. Warltier Modulation of the adaptive response to myocardial ischemia by coexisting disease Am J Physiol Heart Circ Physiol, June 1, 1999; 276(6): H2268 - H2270. [Full Text] [PDF] |
||||
![]() |
K. N. Garratt, P. A. Brady, N. L. Hassinger, D. E. Grill, A. Terzic, and D. R. Holmes Jr. Sulfonylurea drugs increase early mortality in patients with diabetes mellitus after direct angioplasty for acute myocardial infarction J. Am. Coll. Cardiol., January 1, 1999; 33(1): 119 - 124. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. B. Investigators Influence of Diabetes on 5-Year Mortality and Morbidity in a Randomized Trial Comparing CABG and PTCA in Patients With Multivessel Disease : The Bypass Angioplasty Revascularization Investigation (BARI) Circulation, September 16, 1997; 96(6): 1761 - 1769. [Abstract] [Full Text] |
||||












