European Heart Journal Advance Access published online on December 9, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn531
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Self-estimated physical functioning poorly predicts actual exercise capacity in adolescents and adults with congenital heart disease
Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Technische Universität München, Lazarettstr. 36, D-80636 München, Germany
Received 19 March 2008; revised 16 October 2008; accepted 18 November 2008.
* Corresponding author. Tel: +49 89 1218 1650, Fax: +49 89 1218 3013, Email: alexander.gratz{at}o2online.de; Hager{at}dhm.mhn.de
Aims: The aim of this study is to compare self-reported health-related quality-of-life (HRQoL) with the objective of exercise performance in patients with congenital heart disease (CHD) according to diagnosis.
Methods and results: 564 patients (255 females, 14–73 years) with various CHD (62 shunt, 66 left heart obstruction, 33 PS/PR, 47 Ebstein, 96 Fallot, 98 TGA after atrial switch, 38 other TGA, 31 Fontan, 32 palliated/native cyanotic, 61 others) and a group of 53 healthy controls (18 females, 14–57 years) completed a QoL questionnaire (SF-36) and performed a symptom-limited cardiopulmonary exercise test. Despite several limitations at exercise (P = 1.30 x 10–33), patients only reported reductions in HRQoL concerning physical functioning (P = 4.41 x 10–15) and general health (P = 6.17 x 10–5) and not psychosocial aspects. This could be confirmed in all diagnostic subgroups. Correlation to peak oxygen uptake was found in physical functioning (r = 0.435, P = 1.72 x 10–27) and general health (r = 0.275, P = 3.79 x 10–11). However, there was severe overestimation of physical functioning in most patients when compared with actual exercise test results.
Conclusion: Patients with CHD rate their HRQoL impaired only in physical functioning and general health and not in any psychosocial aspect. Self-estimated physical functioning poorly predicts actual exercise capacity.
Key Words: Congenital heart disease Quality of life Cardiopulmonary exercise testing
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S. Glaser, C. Schaper, R. Ewert, and B. Koch Peak oxygen uptake and exercise capacity: a reliable predictor of quality of life? Eur. Heart J., July 1, 2009; 30(13): 1674 - 1674. [Full Text] [PDF] |
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A. Gratz, J. Hess, and A. Hager Peak oxygen uptake and exercise capacity: a reliable predictor of quality of life?: reply Eur. Heart J., July 1, 2009; 30(13): 1674 - 1675. [Full Text] [PDF] |
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