Skip Navigation



European Heart Journal Advance Access published online on September 14, 2009
European Heart Journal, doi:10.1093/eurheartj/ehp375
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bjerregaard, L. J.
Right arrow Articles by Schmidt, E. B.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bjerregaard, L. J.
Right arrow Articles by Schmidt, E. B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Fish intake and acute coronary syndrome

Lone J. Bjerregaard1,2,*, Albert M. Joensen1,2, Claus Dethlefsen1,2, Majken K. Jensen1,2,3, Søren P. Johnsen2,3, Anne Tjønneland4, Lars H. Rasmussen1,2, Kim Overvad1,2,3 and Erik B. Schmidt1,2

1 Department of Cardiology, Aalborg Hospital, Aarhus University Hospital, Sdr. Skovvej 15, 9000 Aalborg, Denmark
2 Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
3 Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
4 Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark

Received 13 January 2009; revised 15 July 2009; accepted 14 August 2009 * Corresponding author. Tel: +45 99326893, Fax: +45 99326813, Email: ljb{at}rn.dk

Aims: To study the effect of fish consumption on the risk of acute coronary syndrome (ACS) in healthy subjects.

Methods and results: This Danish follow-up study included 57 053 men and women between 50 and 64 years. Intake of lean and fatty fish was estimated from a detailed and validated food frequency questionnaire. Potential cases of ACS were identified through nationwide medical databases. A total of 1122 cases of ACS were verified during a mean follow-up period of 7.6 years. Among men, intake of fatty fish was associated with a lower risk of ACS. For men in the highest quintile of fish intake compared with the lowest quintile, the hazard ratio was 0.67 (95% confidence interval: 0.53–0.85). The inverse association was observed for intakes >6 g of fatty fish per day with no obvious additional benefit observed for higher intakes. Intake of lean fish was not associated with ACS. There were few cases of ACS and results were not consistent in women.

Conclusion: In conclusion, a modest intake of fatty fish was associated with a lower risk of ACS in middle-aged men, whereas no consistent associations were observed among women.

Key Words: Acute coronary syndrome • Coronary heart disease • Fish • n–3 PUFA • Nutrition • Prospective study • Follow-up study


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.