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European Heart Journal Advance Access published online on November 4, 2009
European Heart Journal, doi:10.1093/eurheartj/ehp433
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis

Francesco Prati1,*, Evelyn Regar2, Gary S. Mintz3, Eloisa Arbustini4, Carlo Di Mario5, Ik-Kyung Jang6, Takashi Akasaka7, Marco Costa8, Giulio Guagliumi9, Eberhard Grube10, Yukio Ozaki11, Fausto Pinto12, Patrick W.J. Serruys2 for the Expert's OCT Review Document

1 Interventional Cardiology, San Giovanni Hospital, Via dell'Amba Aradam, 8, 00184 Rome, Italy
2 Thoraxcenter, University Hospital Rotterdam, Rotterdam, the Netherlands
3 Washington Hospital Center, Washington, DC, USA
4 IRCCS Foundation Policlinico San Matteo, Pavia, Italy
5 Royal Brompton Hospital and Imperial College, London, UK
6 Massachusetts General Hospital, Boston, MA, USA
7 Wakayama Medical University, Wakayama, Japan
8 Medical Center Cleveland, Cleveland, OH, USA
9 Spedali Riuniti, Bergamo, Italy
10 Heart Center Siegburg, Siegburg, Germany
11 Fujita Health University, Fujita, Japan
12 University of Lisbon, Lisbon, Portugal

Received 10 December 2008; revised 30 April 2009; accepted 12 June 2009 * Corresponding author. Tel: +39 06 77 05 53 30, Email: fprati{at}hsangiovanni.roma.it

Optical coherence tomography (OCT) is a novel intravascular imaging modality, based on infrared light emission, that enables a high resolution arterial wall imaging, in the range of 10–20 microns. This feature of OCT allows the visualization of specific components of the atherosclerotic plaques. The aim of the present Expert Review Document is to address the methodology, terminology and clinical applications of OCT for qualitative and quantitative assessment of coronary arteries and atherosclerosis.

Key Words: Atherosclerosis • OCT • Intravascular imaging • Angioplasty


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