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European Heart Journal 2003 24(5):381-383; doi:10.1016/S0195-668X(02)00699-1
Copyright © 2003 by the European Society of Cardiology.
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Editorial

Looking for people at high cardiovascular risk? Look at serum-creatinine

J.F.E Manna,*, I Dulau-Floreab and J Frankeb

a Department of Nephrology and Hypertension, Schwabing General Hospital, LMU, Kolner Platz 1, 80804 Munich, Germany
b German Institute for High Blood Pressure Research, Heidelberg, Germany

* Corresponding author. Tel.: +49-89-3068-2386; fax: +49-89-3068-3917
E-mail address: johannes.mann@kms.mhn.de

The first 10% of the full text of this article appears below.

See doi:10.1016/S1095-668X(02)00526-2for the article to which this editorial refers.

When patients present to hospital with an acute myocardial infarction, the major long-term aims are to preserve myocardial function and to prevent cardiovascular events. To this end and beyond, the corrected interpretation of serum-creatinine as a marker of glomerular filtration rate (GFR) as well as of future cardiovascular and renal events is helpful. In this issue, Hillege and collaborators1 provide compelling evidence for people with acute myocardial infarction (a) that even mildly reduced GFR is highly predictive for the development of heart failure and (b) that ACE inhibition with captopril preserves renal and cardiac function better than placebo over 1 year. The data apply to people without severe heart failure or hypotension . . . [Full Text of this Article]


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Related articles in EHJ:

Accelerated decline and prognostic impact of renal function after myocardial infarction and the benefits of ACE inhibition: the CATS randomized trial
H.L. Hillege, W.H. van Gilst, D.J. van Veldhuisen, G. Navis, D.E. Grobbee, P.A. de Graeff, and D. de Zeeuw
EHJ 2003 24: 412-420. [Abstract] [FREE Full Text]  



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J. J. Brugts, E. Boersma, M. Chonchol, J. W. Deckers, M. Bertrand, W. J. Remme, R. Ferrari, K. Fox, M. L. Simoons, and on behalf of the EUROPA Investigators
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