Skip Navigation

European Heart Journal 2003 24(5):384-390;
Copyright © 2003 by the European Society of Cardiology.
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in EHJ
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (10)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Cleland, J. G.F.
Right arrow Articles by Kaye, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cleland, J. G.F.
Right arrow Articles by Kaye, G.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Editorial

Multi-chamber pacing: a perfect solution for cardiac mechanical dyssynchrony?

John G.F. Clelanda,*, Justin Ghosha, Nasrin K. Khana, Stefano Ghiob, Luigi Tavazzib and Gerry Kayea

a Department of Cardiology, University of Hull, Castle Hill Hospital, Castle Road, Kingston upon Hull HU16 5JQ, UK
b Department of Cardiology, Policlinico S. Matteo, Institute of Care and Research, Pavia, Italy

* Corresponding author. Tel.: +44-1482-624084; fax: +44-1482-624085
E-mail address: j.g.cleland@hull.ac.uk

The first 150 words of the full text of this article appear below.

See doi:10.1016/S1095-668X(02)00475-Xfor the article to which this editorial refers.

When the heart fails, it becomes less efficient, as myocardial energy consumption rises without a corresponding increase in cardiac output. There are many possible reasons for this decline in cardiac efficiency (Fig. 1). Recently, because of the potential value of multi-site pacing, interest has focused on mechanical dyssynchrony, which encompasses a complex array of problems that often coexist in varying degrees along with ‘functional’ mitral regurgitation.1–3


Figure Removed (Available Only in the Full Text)
View larger version (32K):
[in this window]
[in a new window]
 
Fig. 1 Some mechanisms of heart failure causation and progression (usually multiple mechanisms operating simultaneously conspire to cause progression of heart failure).

 
It is likely that mechanical dyssynchrony is common, although precisely how common is unclear, and will depend on the definition and the tools used to measure it. The presence and severity of cardiac dyssynchrony can be assessed directly using imaging techniques or indirectly by measuring time-intervals from a standard 12-lead echocardiography (ECG). ECG . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in EHJ:

Left ventricular remodelling and haemodynamic effects of multisite biventricular pacing in patients with left ventricular systolic dysfunction and activation disturbances in sinus rhythm: sub-study of the MUSTIC (Multisite Stimulationin Cardiomyopathies) trial
A. Duncan, D. Wait, D. Gibson, and J.-C. Daubert
EHJ 2003 24: 430-441. [Abstract] [FREE Full Text]  



This article has been cited by other articles:


Home page
J Am Coll CardiolHome page
C. Leclercq, F. Gadler, W. Kranig, S. Ellery, D. Gras, A. Lazarus, J. Clementy, E. Boulogne, J.-C. Daubert, and for the TRIP-HF (Triple Resynchronization In Paced
A Randomized Comparison of Triple-Site Versus Dual-Site Ventricular Stimulation in Patients With Congestive Heart Failure
J. Am. Coll. Cardiol., April 15, 2008; 51(15): 1455 - 1462.
[Abstract] [Full Text] [PDF]


Home page
Eur J Heart FailHome page
J.G.F. Cleland, J.C. Daubert, E. Erdmann, N. Freemantle, D. Gras, L. Kappenberger, W. Klein, L. Tavazzi, and On behalf of the CARE-HF study Steering Committee
Baseline characteristics of patients recruited into the CARE-HF study
Eur J Heart Fail, March 2, 2005; 7(2): 205 - 214.
[Abstract] [Full Text] [PDF]


Home page
Eur J Heart FailHome page
K. Lalukota, J. G.F. Cleland, L. Ingle, A. L. Clark, and A. P. Coletta
Clinical trials update from the Heart Failure Society of America: EMOTE, HERB-CHF, BEST genetic sub-study and RHYTHM-ICD
Eur J Heart Fail, December 1, 2004; 6(7): 953 - 955.
[Abstract] [Full Text] [PDF]


Home page
Eur J Heart FailHome page
J. G.F. Cleland, J. Ghosh, N. Freemantle, G. C. Kaye, M. Nasir, A. L. Clark, and A. P. Coletta
Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-Lipids and cardiac resynchronisation therapy in heart failure
Eur J Heart Fail, June 1, 2004; 6(4): 501 - 508.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. G. F. Cleland and A. L. Clark
Delivering the cumulative benefits of triple therapy to improve outcomes in heart failure: Too many cooks will spoil the broth
J. Am. Coll. Cardiol., October 1, 2003; 42(7): 1234 - 1237.
[Full Text] [PDF]


Home page
Eur J Heart FailHome page
J. G.F. Cleland, A. P. Coletta, N. Nikitin, A. Louis, and A. Clark
Update of clinical trials from the American College of Cardiology 2003. EPHESUS, SPORTIF-III, ASCOT, COMPANION, UK-PACE and T-wave alternans
Eur J Heart Fail, June 1, 2003; 5(3): 391 - 398.
[Abstract] [Full Text] [PDF]