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European Heart Journal 2004 25(15):1281-1283; doi:10.1016/j.ehj.2004.06.012
Copyright © 2004 by the European Society of Cardiology.
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Editorial

Obstructive sleep apnoea and plasma homocysteine: an overview

Mikolaj Winnickia,b,1 and Paolo Palatinia,*

a University of Padova, Padua, Italy
b Medical University of Gdansk, Poland

* Correspondence to: Professor Paolo Palatini, M.D., Clinica Medica 4 – University of Padova via Giustiniani, 2-35128 Padova, Italy. Tel.: +39-49-8212278; fax: +39-49-8754179
E-mail address: palatini@unipd.it

The first 150 words of the full text of this article appear below.

This editorial refers to "Plasma homocysteine in obstructive sleep apnoea"2 by A. Svatikova et al. on page 1325

Sleep-disordered breathing syndromes are recognised as an important factor for increased morbidity in cardiovascular diseases.1,2 They are characterised by the presence of repetitive episodes of ventilation cessation (apnoea), or airflow reduction (hypopnoea), or both during sleep. This leads to hypoxia, hyperkapnia, several-fold increase in chemoreflex-activated sympathetic activity with consequent peaks in blood pressure exceeding 200/100 mmHg, increased heart rate, frequent arousals, and sleep fragmentation.

In the diagnosis of sleep-related disorders, apnoea is defined as cessation of airflow for a minimum of 10 s while hypopnoea is defined as at least a 30% reduction in airflow accompanied by at least a 4% decrease in oxygen saturation.3 The sleep apnoea syndromes are divided into obstructive (OSA) and central (CSA) types. OSA is characterised by apnoeas associated with continuous respiratory efforts, despite cessation of airflow, . . . [Full Text of this Article]


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Related articles in EHJ:

Plasma homocysteine in obstructive sleep apnoea
Anna Svatikova, Robert Wolk, Mark J Magera, Abu S Shamsuzzaman, Bradley G Phillips, and Virend K Somers
EHJ 2004 25: 1325-1329. [Abstract] [Full Text]  



This article has been cited by other articles:


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A. Svatikova, R. Wolk, M. J. Magera, A. S. Shamsuzzaman, B. G. Phillips, and V. K. Somers
Obstructive sleep apnoea and plasma homocysteine: reply
Eur. Heart J., October 2, 2005; 26(20): 2210 - 2211.
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L. Lavie and P. Lavie
Obstructive sleep apnoea and plasma homocysteine
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