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European Heart Journal 2004 25(17):1473-1474; doi:10.1016/j.ehj.2004.07.001
Copyright © 2004 by the European Society of Cardiology.
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Editorial

Transient myocardial ischaemia: new questions about autonomic responses

Robert Sheldon*

Libin Cardiovascular Institute, University of Calgary, Calgary, Alta., Canada

* Correspondence to: Dr. Robert Sheldon, Cardiovascular Research Group, Libin Cardiovascular Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta., Canada T2N 4N1. Tel.: +1-403-220-8191; fax: +1-403-270-0313 (E-mail: sheldon@ucalgary.ca).

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This editorial refers to "Changes in autonomic nervous system activity: spontaneous versus balloon-induced myocardial ischaemia"{dagger} by O. Manfrini et al. on page 1502

In this issue of the Journal Manfrini et al.,1 demonstrate that radically different autonomic profiles accompany episodes of spontaneous myocardial ischaemia compared to myocardial ischaemia in the same patient. Practicing cardiologists have known for decades that the location of myocardial ischaemia determines the pattern of autonomic response. For example, acute transmural anterior wall myocardial infarction is often accompanied by sympathetic activation, sinus tachycardia, and relative hypertension, while inferior wall infarction is accompanied by sinus bradycardia and hypotension. Given that heart rate variability is assumed to shed insight into the balance between vagal and sympathetic tone,2 this led to . . . [Full Text of this Article]


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Related articles in EHJ:

Changes in autonomic nervous system activity: spontaneous versus balloon-induced myocardial ischaemia
Olivia Manfrini, Gianluigi Morgagni, Carmine Pizzi, Fiorella Fontana, and Raffaele Bugiardini
EHJ 2004 25: 1502-1508. [Abstract] [Full Text]