Copyright © 2004 by the European Society of Cardiology.
Letter to the Editor
Reply: ß-Blocker effects on sexual function
Cardiovascular Research Unit, Department of Medical Sciences, San Raffaele Roma, Tosinvest Sanità, via della Pisana 235, 00163 Rome, Italy
* Corresponding author. Tel.: +39-6660581; fax: +39-69636715
E-mail address: antosilv@hotmail.com
Received 8 December 2003; accepted 12 December 2003
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Dear Sir
In their letter, Jaarsma et al. raised some methodological concerns regarding the study we conducted on the effect of ß-blockers on erectile dysfunction. These criticisms are in our view the result of a misinterpretation of the manuscript.
The first criticism is related to the small number of patients included in each group. However the number of patients required in clinical trials depends on the incidence of the events in the population studied and on the expected