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European Heart Journal Advance Access originally published online on May 18, 2005
European Heart Journal 2005 26(11):1115-1140; doi:10.1093/eurheartj/ehi204
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005)

The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology

Authors/Task Force Members, Karl Swedberg, Chairperson, Göteborg (Sweden)* Writing Committee:, John Cleland, Hull (UK), Henry Dargie, Glasgow (UK), Helmut Drexler, Hannover (Germany), Ferenc Follath, Zurich (Switzerland), Michel Komajda, Paris (France), Luigi Tavazzi, Pavia (Italy), Otto A. Smiseth, Oslo (Norway) Other Contributors, Antonello Gavazzi, Bergamo (Italy), Axel Haverich, Hannover (Germany), Arno Hoes, Utrecht (The Netherlands), Tiny Jaarsma, Gronigen (The Netherlands), Jerzy Korewicki, Warsaw (Poland), Samuel Lévy, Marseille (France), Cecilia Linde, Stockholm (Sweden), José-Luis Lopez-Sendon, Madrid (Spain), Markku S. Nieminen, Helsinki (Finland), Luc Piérard, Liège (Belgium), Willem J. Remme, Rhoon (The Netherlands)

* Corresponding author. Chairperson: Karl Swedberg, Sahlgrenska Academy at the Göteborg University, Department of Medicine, Sahlgrenska University Hospital Östra, SE-416 85 Göteborg, Sweden. Tel.: +46 31 3434078; fax: +46 31 258933. E-mail address: karl.swedberg@hjl.gu.se

ESC Committee for Practice Guidelines (CPG), Silvia G. Priori (Chairperson) (Italy), Jean-Jacques Blanc (France), Andrzej Budaj (Poland), John Camm (UK), Veronica Dean (France), Jaap Deckers (The Netherlands), Kenneth Dickstein (Norway), John Lekakis (Greece), Keith McGregor (France), Marco Metra (Italy), João Morais (Portugal), Ady Osterspey (Germany), Juan Tamargo (Spain), José Luis Zamorano (Spain)
Document Reviewers, Marco Metra (CPG Review Coordinator) (Italy), Michael Böhm (Germany), Alain Cohen-Solal (France), Martin Cowie (UK), Ulf Dahlström (Sweden), Kenneth Dickstein (Norway), Gerasimos S. Filippatos (Greece), Edoardo Gronda (Italy), Richard Hobbs (UK), John K. Kjekshus (Norway), John McMurray (UK), Lars Rydén (Sweden), Gianfranco Sinagra (Italy), Juan Tamargo (Spain), Michal Tendera (Poland), Dirk van Veldhuisen (The Netherlands), Faiez Zannad (France)

The first 150 words of the full text of this article appear below.

Preamble

Guidelines and Expert Consensus Documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making.

A great number of Guidelines and Expert Consensus Documents have been issued in recent years by the European Society of Cardiology (ESC) and by different organizations and other related societies. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing Guidelines and Expert Consensus Documents.

In spite of the fact that standards for issuing good quality Guidelines and Expert Consensus Documents are well defined, recent surveys of Guidelines and Expert Consensus Documents published . . . [Full Text of this Article]

Diagnosis of chronic heart failure

Introduction

Methodology
Epidemiology

Descriptive terms in heart failure

Acute vs. chronic heart failure
Systolic vs. diastolic heart failure
Other descriptive terms in heart failure
Definition of chronic heart failure
Aspects of the pathophysiology of the symptoms of heart failure relevant to diagnosis

Possible methods for the diagnosis of heart failure in clinical practice

Symptoms and signs in the diagnosis of heart failure
Symptoms and the severity of heart failure
Electrocardiogram
The chest X-ray
Haematology and biochemistry
Natriuretic peptides
Echocardiography
Assessment of LV diastolic function
Diagnostic criteria of diastolic dysfunction
Additional non-invasive tests to be considered
Cardiac magnetic resonance imaging (CMR)
Pulmonary function
Exercise testing
Invasive investigation
Cardiac catheterization
Tests of neuroendocrine evaluations other than natriuretic peptides
Holter electrocardiography: ambulatory ECG and long-time ECG recording (LTER)
Requirements for the diagnosis of heart failure in clinical practice
Prognostication
Treatment of heart failure

Aims of treatment in heart failure

Prevention of heart failure

Management of chronic heart failure

Non-pharmacological management

General advice and measures
Educating patients and family
Weight monitoring
Dietary measures
Sodium
Fluids
Alcohol
Obesity
Abnormal weight loss
Smoking
Travelling
Sexual activity
Advice on immunizations
Drug counselling
Drugs to avoid or beware
Rest, exercise, and exercise training
Rest
Exercise
Pharmacological therapy

Angiotensin-converting enzyme inhibitors
ACE-inhibitors in asymptomatic left ventricular dysfunction
ACE-inhibitors in symptomatic heart failure
Diuretics
Loop diuretics, thiazides, and metolazone
Potassium-sparing diuretics
Beta-adrenoceptor antagonists
Initiation of therapy
Aldosterone receptor antagonists
Angiotensin II receptor blockers
Dosing
Cardiac glycosides
Digoxin
Vasodilator agents in chronic heart failure
Hydralazine-isosorbide dinitrate
Nitrates
Alpha-adrenergic blocking drugs
Calcium antagonists
Nesiritide
Positive inotropic therapy
Anti-thrombotic agents
Anti-arrhythmics
Class I anti-arrhythmics
Class II anti-arrhythmics
Class III anti-arrhythmics
Oxygen therapy
Surgery and devices

Revascularization procedures, mitral valve surgery, and ventricular restoration
Revascularization
Mitral valve surgery
Left ventricular restoration
LV aneurysmectomy
Cardiomyoplasty
Partial left ventriculectomy (Batista operation)
External ventricular restoration
Pacemakers
Implantable cardioverter defibrillators
Heart replacement therapies: heart transplantation, ventricular assist devices, and artificial heart
Heart transplantation
Ventricular assist devices and artificial heart
Ultrafiltration
Choice and timing of pharmacological therapy
Asymptomatic left ventricular systolic dysfunction
Symptomatic left ventricular systolic dysfunction: heart failure NYHA class II (Figure 4)
Without signs of fluid retention
With signs of fluid retention
Worsening heart failure (Figure 3)
End-stage heart failure (patients who persist in NYHA IV despite optimal treatment and proper diagnosis (Figure 4)
Management of heart failure with preserved left ventricular ejection fraction
Pharmacological therapy of heart failure with PLVEF or diastolic dysfunction
Heart failure treatment in the elderly

ACE-inhibitors and ARBs
Diuretic therapy
Beta-blockers
Cardiac glycosides
Vasodilator agents
Arrhythmias
Ventricular arrhythmias
Atrial fibrillation
Symptomatic systolic left ventricular dysfunction and concomitant angina or hypertension

Care and follow-up


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J Am Coll CardiolHome page
J. E.A. Blair, F. Zannad, M. A. Konstam, T. Cook, B. Traver, J. C. Burnett Jr, L. Grinfeld, H. Krasa, A. P. Maggioni, C. Orlandi, et al.
Continental Differences in Clinical Characteristics, Management, and Outcomes in Patients Hospitalized With Worsening Heart Failure: Results From the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Program
J. Am. Coll. Cardiol., November 11, 2008; 52(20): 1640 - 1648.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
P. A. Poole-Wilson
Global Differences in the Outcome of Heart Failure: Implications for Clinical Practice
J. Am. Coll. Cardiol., November 11, 2008; 52(20): 1649 - 1651.
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Scand J Public HealthHome page
N. K. Nissen, M. Madsen, M. Kjoller, S. B. Waldorff, and A.-D. Olsen Zwisler
Are hospitals also for relatives? A survey of hospitals' activities regarding relatives of cardiac patients
Scand J Public Health, November 1, 2008; 36(8): 827 - 831.
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QJMHome page
P. Ray, S. Delerme, P. Jourdain, and C. Chenevier-Gobeaux
Differential diagnosis of acute dyspnea: the value of B natriuretic peptides in the emergency department
QJM, November 1, 2008; 101(11): 831 - 843.
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Eur J Heart FailHome page
C. Jarnert, A. Melcher, K. Caidahl, H. Persson, L. Ryden, and M. J. Eriksson
Left atrial velocity vector imaging for the detection and quantification of left ventricular diastolic function in type 2 diabetes
Eur J Heart Fail, November 1, 2008; 10(11): 1080 - 1087.
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Eur J Heart FailHome page
P. A. Mehta, S. W. Dubrey, H. F. McIntyre, D. M. Walker, S. M.C. Hardman, G. C. Sutton, T. A. McDonagh, and M. R. Cowie
Mode of death in patients with newly diagnosed heart failure in the general population
Eur J Heart Fail, November 1, 2008; 10(11): 1108 - 1116.
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Clin. Chem.Home page
J. P. Goetze, U. Dahlstrom, J. F. Rehfeld, and U. Alehagen
Impact of Epitope Specificity and Precursor Maturation in Pro-B-Type Natriuretic Peptide Measurement
Clin. Chem., November 1, 2008; 54(11): 1780 - 1787.
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J Am Coll CardiolHome page
L. Di Biase, M. Gasparini, M. Lunati, M. Santini, M. Landolina, G. Boriani, A. Curnis, M. Bocchiardo, A. Vincenti, A. Denaro, et al.
Antiarrhythmic Effect of Reverse Ventricular Remodeling Induced by Cardiac Resynchronization Therapy: The InSync ICD (Implantable Cardioverter-Defibrillator) Italian Registry
J. Am. Coll. Cardiol., October 28, 2008; 52(18): 1442 - 1449.
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CirculationHome page
B. Pitt, G. Bakris, L. M. Ruilope, L. DiCarlo, R. Mukherjee, and on Behalf of the EPHESUS Investigators
Serum Potassium and Clinical Outcomes in the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS)
Circulation, October 14, 2008; 118(16): 1643 - 1650.
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Eur Heart JHome page
T. Stanton, N. M. Hawkins, K. J. Hogg, N. E.R. Goodfield, M. C. Petrie, and J. J.V. McMurray
How should we optimize cardiac resynchronization therapy?
Eur. Heart J., October 2, 2008; 29(20): 2458 - 2472.
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Contin Educ Anaesth Crit Care PainHome page
A. Kotze and S. J. Howell
Heart failure: pathophysiology, risk assessment, community management and anaesthesia
CEACCP, October 1, 2008; 8(5): 161 - 166.
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Eur Heart JHome page
Authors/Task Force Members, K. Dickstein, A. Cohen-Solal, G. Filippatos, J. J.V. McMurray, P. Ponikowski, P. A. Poole-Wilson, A. Stromberg, D. J. van Veldhuisen, D. Atar, et al.
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
Eur. Heart J., October 1, 2008; 29(19): 2388 - 2442.
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Eur J Heart FailHome page
K. Dickstein, A. Cohen-Solal, G. Filippatos, J. J.V. McMurray, P. Ponikowski, P. A. Poole-Wilson, A. Stromberg, D. J. van Veldhuisen, D. Atar, A. W. Hoes, et al.
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
Eur J Heart Fail, October 1, 2008; 10(10): 933 - 989.
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Eur J Heart FailHome page
L. Erhardt, M. Komajda, F.D. R. Hobbs, and J. Soler-Soler
Cardiologists' awareness and perceptions of guidelines for chronic heart failure. The ADDress your Heart survey
Eur J Heart Fail, October 1, 2008; 10(10): 1020 - 1025.
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ThoraxHome page
B R O'Driscoll, L S Howard, A G Davison, and on behalf of the British Thoracic Society
BTS guideline for emergency oxygen use in adult patients
Thorax, October 1, 2008; 63(Suppl_6): vi1 - vi68.
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Eur Heart JHome page
M. Huelsmann, S. Neuhold, G. Strunk, D. Moertl, R. Berger, R. Prager, H. Abrahamian, M. Riedl, R. Pacher, A. Luger, et al.
NT-proBNP has a high negative predictive value to rule-out short-term cardiovascular events in patients with diabetes mellitus
Eur. Heart J., September 2, 2008; 29(18): 2259 - 2264.
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J Telemed TelecareHome page
C. Masella, P. Zanaboni, F. Di Stasi, S. Gilardi, P. Ponzi, and S. Valsecchi
Assessment of a remote monitoring system for implantable cardioverter defibrillators
J Telemed Telecare, September 1, 2008; 14(6): 290 - 294.
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Circ Heart FailHome page
G. Parati, G. Malfatto, S. Boarin, G. Branzi, G. Caldara, A. Giglio, G. Bilo, G. Ongaro, A. Alter, B. Gavish, et al.
Device-Guided Paced Breathing in the Home Setting: Effects on Exercise Capacity, Pulmonary and Ventricular Function in Patients With Chronic Heart Failure: A Pilot Study
Circ Heart Fail, September 1, 2008; 1(3): 178 - 183.
[Abstract] [Full Text] [PDF]