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European Heart Journal Advance Access originally published online on May 18, 2005
European Heart Journal 2005 26(11):1115-1140; doi:10.1093/eurheartj/ehi204
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005)

The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology

Authors/Task Force Members, Karl Swedberg, Chairperson, Göteborg (Sweden)* Writing Committee:, John Cleland, Hull (UK), Henry Dargie, Glasgow (UK), Helmut Drexler, Hannover (Germany), Ferenc Follath, Zurich (Switzerland), Michel Komajda, Paris (France), Luigi Tavazzi, Pavia (Italy), Otto A. Smiseth, Oslo (Norway) Other Contributors, Antonello Gavazzi, Bergamo (Italy), Axel Haverich, Hannover (Germany), Arno Hoes, Utrecht (The Netherlands), Tiny Jaarsma, Gronigen (The Netherlands), Jerzy Korewicki, Warsaw (Poland), Samuel Lévy, Marseille (France), Cecilia Linde, Stockholm (Sweden), José-Luis Lopez-Sendon, Madrid (Spain), Markku S. Nieminen, Helsinki (Finland), Luc Piérard, Liège (Belgium), Willem J. Remme, Rhoon (The Netherlands)

* Corresponding author. Chairperson: Karl Swedberg, Sahlgrenska Academy at the Göteborg University, Department of Medicine, Sahlgrenska University Hospital Östra, SE-416 85 Göteborg, Sweden. Tel.: +46 31 3434078; fax: +46 31 258933. E-mail address: karl.swedberg@hjl.gu.se

ESC Committee for Practice Guidelines (CPG), Silvia G. Priori (Chairperson) (Italy), Jean-Jacques Blanc (France), Andrzej Budaj (Poland), John Camm (UK), Veronica Dean (France), Jaap Deckers (The Netherlands), Kenneth Dickstein (Norway), John Lekakis (Greece), Keith McGregor (France), Marco Metra (Italy), João Morais (Portugal), Ady Osterspey (Germany), Juan Tamargo (Spain), José Luis Zamorano (Spain)
Document Reviewers, Marco Metra (CPG Review Coordinator) (Italy), Michael Böhm (Germany), Alain Cohen-Solal (France), Martin Cowie (UK), Ulf Dahlström (Sweden), Kenneth Dickstein (Norway), Gerasimos S. Filippatos (Greece), Edoardo Gronda (Italy), Richard Hobbs (UK), John K. Kjekshus (Norway), John McMurray (UK), Lars Rydén (Sweden), Gianfranco Sinagra (Italy), Juan Tamargo (Spain), Michal Tendera (Poland), Dirk van Veldhuisen (The Netherlands), Faiez Zannad (France)

The first 150 words of the full text of this article appear below.

Preamble

Guidelines and Expert Consensus Documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making.

A great number of Guidelines and Expert Consensus Documents have been issued in recent years by the European Society of Cardiology (ESC) and by different organizations and other related societies. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing Guidelines and Expert Consensus Documents.

In spite of the fact that standards for issuing good quality Guidelines and Expert Consensus Documents are well defined, recent surveys of Guidelines and Expert Consensus Documents published . . . [Full Text of this Article]

Diagnosis of chronic heart failure

Introduction

Methodology
Epidemiology

Descriptive terms in heart failure

Acute vs. chronic heart failure
Systolic vs. diastolic heart failure
Other descriptive terms in heart failure
Definition of chronic heart failure
Aspects of the pathophysiology of the symptoms of heart failure relevant to diagnosis

Possible methods for the diagnosis of heart failure in clinical practice

Symptoms and signs in the diagnosis of heart failure
Symptoms and the severity of heart failure
Electrocardiogram
The chest X-ray
Haematology and biochemistry
Natriuretic peptides
Echocardiography
Assessment of LV diastolic function
Diagnostic criteria of diastolic dysfunction
Additional non-invasive tests to be considered
Cardiac magnetic resonance imaging (CMR)
Pulmonary function
Exercise testing
Invasive investigation
Cardiac catheterization
Tests of neuroendocrine evaluations other than natriuretic peptides
Holter electrocardiography: ambulatory ECG and long-time ECG recording (LTER)
Requirements for the diagnosis of heart failure in clinical practice
Prognostication
Treatment of heart failure

Aims of treatment in heart failure

Prevention of heart failure

Management of chronic heart failure

Non-pharmacological management

General advice and measures
Educating patients and family
Weight monitoring
Dietary measures
Sodium
Fluids
Alcohol
Obesity
Abnormal weight loss
Smoking
Travelling
Sexual activity
Advice on immunizations
Drug counselling
Drugs to avoid or beware
Rest, exercise, and exercise training
Rest
Exercise
Pharmacological therapy

Angiotensin-converting enzyme inhibitors
ACE-inhibitors in asymptomatic left ventricular dysfunction
ACE-inhibitors in symptomatic heart failure
Diuretics
Loop diuretics, thiazides, and metolazone
Potassium-sparing diuretics
Beta-adrenoceptor antagonists
Initiation of therapy
Aldosterone receptor antagonists
Angiotensin II receptor blockers
Dosing
Cardiac glycosides
Digoxin
Vasodilator agents in chronic heart failure
Hydralazine-isosorbide dinitrate
Nitrates
Alpha-adrenergic blocking drugs
Calcium antagonists
Nesiritide
Positive inotropic therapy
Anti-thrombotic agents
Anti-arrhythmics
Class I anti-arrhythmics
Class II anti-arrhythmics
Class III anti-arrhythmics
Oxygen therapy
Surgery and devices

Revascularization procedures, mitral valve surgery, and ventricular restoration
Revascularization
Mitral valve surgery
Left ventricular restoration
LV aneurysmectomy
Cardiomyoplasty
Partial left ventriculectomy (Batista operation)
External ventricular restoration
Pacemakers
Implantable cardioverter defibrillators
Heart replacement therapies: heart transplantation, ventricular assist devices, and artificial heart
Heart transplantation
Ventricular assist devices and artificial heart
Ultrafiltration
Choice and timing of pharmacological therapy
Asymptomatic left ventricular systolic dysfunction
Symptomatic left ventricular systolic dysfunction: heart failure NYHA class II (Figure 4)
Without signs of fluid retention
With signs of fluid retention
Worsening heart failure (Figure 3)
End-stage heart failure (patients who persist in NYHA IV despite optimal treatment and proper diagnosis (Figure 4)
Management of heart failure with preserved left ventricular ejection fraction
Pharmacological therapy of heart failure with PLVEF or diastolic dysfunction
Heart failure treatment in the elderly

ACE-inhibitors and ARBs
Diuretic therapy
Beta-blockers
Cardiac glycosides
Vasodilator agents
Arrhythmias
Ventricular arrhythmias
Atrial fibrillation
Symptomatic systolic left ventricular dysfunction and concomitant angina or hypertension

Care and follow-up


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Ann. Thorac. Surg.Home page
B. Hansky, J. Vogt, A. Zittermann, H. Guldner, J. Heintze, U. Schulz, D. Horstkotte, G. Tenderich, and R. Korfer
Cardiac resynchronization therapy: long-term alternative to cardiac transplantation?
Ann. Thorac. Surg., February 1, 2009; 87(2): 432 - 438.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
N. M. Hawkins, M. C. Petrie, P. S. Jhund, G. W. Chalmers, F. G. Dunn, and J. J.V. McMurray
Heart failure and chronic obstructive pulmonary disease: diagnostic pitfalls and epidemiology
Eur J Heart Fail, February 1, 2009; 11(2): 130 - 139.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
L. Frankenstein, C. Zugck, D. Schellberg, M. Nelles, H. Froehlich, H. Katus, and A. Remppis
Prevalence and prognostic significance of adrenergic escape during chronic {beta}-blocker therapy in chronic heart failure
Eur J Heart Fail, February 1, 2009; 11(2): 178 - 184.
[Abstract] [Full Text] [PDF]


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Fam PractHome page
J. C Kelder, F. H Rutten, and A. W Hoes
Clinically relevant diagnostic research in primary care: the example of B-type natriuretic peptides in the detection of heart failure
Fam. Pract., February 1, 2009; 26(1): 69 - 74.
[Abstract] [Full Text] [PDF]


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JAMAHome page
M. Pfisterer, P. Buser, H. Rickli, M. Gutmann, P. Erne, P. Rickenbacher, A. Vuillomenet, U. Jeker, P. Dubach, H. Beer, et al.
BNP-Guided vs Symptom-Guided Heart Failure Therapy: The Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) Randomized Trial
JAMA, January 28, 2009; 301(4): 383 - 392.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
B. A. Koplan, A. J. Kaplan, S. Weiner, P. W. Jones, M. Seth, and S. A. Christman
Heart failure decompensation and all-cause mortality in relation to percent biventricular pacing in patients with heart failure is a goal of 100% biventricular pacing necessary?
J. Am. Coll. Cardiol., January 27, 2009; 53(4): 355 - 360.
[Abstract] [Full Text] [PDF]


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Arch Intern MedHome page
G. H. Gislason, J. N. Rasmussen, S. Z. Abildstrom, T. K. Schramm, M. L. Hansen, E. L. Fosbol, R. Sorensen, F. Folke, P. Buch, N. Gadsboll, et al.
Increased Mortality and Cardiovascular Morbidity Associated With Use of Nonsteroidal Anti-inflammatory Drugs in Chronic Heart Failure
Arch Intern Med, January 26, 2009; 169(2): 141 - 149.
[Abstract] [Full Text] [PDF]


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pdiHome page
C. Basile, D. Chimienti, A. Bruno, S. Cocola, P. Libutti, A. Teutonico, and F. Cazzato
Efficacy of Peritoneal Dialysis with Icodextrin in the Long-Term Treatment of Refractory Congestive Heart Failure
Perit. Dial. Int., January 1, 2009; 29(1): 116 - 118.
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Eur Heart JHome page
J. Rosenberg, M. Schou, F. Gustafsson, J. Badskjaer, and P. Hildebrandt
Prognostic threshold levels of NT-proBNP testing in primary care
Eur. Heart J., January 1, 2009; 30(1): 66 - 73.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
P. de Groote, R. Isnard, P. Clerson, G. Jondeau, M. Galinier, P. Assyag, N. Demil, A. Ducardonnet, J.-F. Thebaut, and M. Komajda
Improvement in the management of chronic heart failure since the publication of the updated guidelines of the European Society of Cardiology: The Impact-Reco Programme
Eur J Heart Fail, January 1, 2009; 11(1): 85 - 91.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
U. Dahlstrom, J. Hakansson, K. Swedberg, and A. Waldenstrom
Adequacy of diagnosis and treatment of chronic heart failure in primary health care in Sweden
Eur J Heart Fail, January 1, 2009; 11(1): 92 - 98.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
T. Jaarsma, K. F. Arestedt, J. Martensson, K. Dracup, and A. Stromberg
The European Heart Failure Self-care Behaviour scale revised into a nine-item scale (EHFScB-9): a reliable and valid international instrument
Eur J Heart Fail, January 1, 2009; 11(1): 99 - 105.
[Abstract] [Full Text] [PDF]


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Eur J EchocardiogrHome page
E. Donal, C. De Place, G. Kervio, F. Bauer, R. Gervais, C. Leclercq, P. Mabo, and J.-C. Daubert
Mitral regurgitation in dilated cardiomyopathy: value of both regional left ventricular contractility and dyssynchrony
Eur J Echocardiogr, January 1, 2009; 10(1): 133 - 138.
[Abstract] [Full Text] [PDF]


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The OncologistHome page
M. Martin, F. J. Esteva, E. Alba, B. Khandheria, L. Perez-Isla, J. A. Garcia-Saenz, A. Marquez, P. Sengupta, and J. Zamorano
Minimizing Cardiotoxicity While Optimizing Treatment Efficacy with Trastuzumab: Review and Expert Recommendations
Oncologist, January 1, 2009; 14(1): 1 - 11.
[Abstract] [Full Text] [PDF]


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ESC Textbook of Cardiovascular MedicineHome page
S. Hoeks and D. Poldermans
CHAPTER 34 Non-cardiac Surgery in Cardiac Patients
ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
C. Linde, W. T. Abraham, M. R. Gold, M. St. John Sutton, S. Ghio, C. Daubert, and REVERSE (REsynchronization reVErses Remodeling in
Randomized Trial of Cardiac Resynchronization in Mildly Symptomatic Heart Failure Patients and in Asymptomatic Patients With Left Ventricular Dysfunction and Previous Heart Failure Symptoms
J. Am. Coll. Cardiol., December 2, 2008; 52(23): 1834 - 1843.
[Abstract] [Full Text] [PDF]


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CirculationHome page
S. Stewart, D. Wilkinson, C. Hansen, V. Vaghela, R. Mvungi, J. McMurray, and K. Sliwa
Predominance of Heart Failure in the Heart of Soweto Study Cohort: Emerging Challenges for Urban African Communities
Circulation, December 2, 2008; 118(23): 2360 - 2367.
[Abstract] [Full Text] [PDF]


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Proc Am Thorac SocHome page
R. Rodriguez-Roisin and J. B. Soriano
Chronic Obstructive Pulmonary Disease with Lung Cancer and/or Cardiovascular Disease
Proceedings of the ATS, December 1, 2008; 5(8): 842 - 847.
[Abstract] [Full Text] [PDF]


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Proc Am Thorac SocHome page
F. Luppi, F. Franco, B. Beghe, and L. M. Fabbri
Treatment of Chronic Obstructive Pulmonary Disease and Its Comorbidities
Proceedings of the ATS, December 1, 2008; 5(8): 848 - 856.
[Abstract] [Full Text] [PDF]


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Eur Heart JHome page
Authors/Task Force Members, F. Van de Werf, J. Bax, A. Betriu, C. Blomstrom-Lundqvist, F. Crea, V. Falk, G. Filippatos, K. Fox, K. Huber, et al.
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology:
Eur. Heart J., December 1, 2008; 29(23): 2909 - 2945.
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Eur J Heart FailHome page
H.-M. Cheng, W.-C. Yu, S.-H. Sung, K.-L. Wang, S.-Y. Chuang, and C.-H. Chen
Usefulness of systolic time intervals in the identification of abnormal ventriculo-arterial coupling in stable heart failure patients
Eur J Heart Fail, December 1, 2008; 10(12): 1192 - 1200.
[Abstract] [Full Text] [PDF]


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Eur J Heart FailHome page
S. Stork, H. W. Hense, C. Zentgraf, I. Uebelacker, R. Jahns, G. Ertl, and C. E. Angermann
Pharmacotherapy according to treatment guidelines is associated with lower mortality in a community-based sample of patients with chronic heart failure A prospective cohort study
Eur J Heart Fail, December 1, 2008; 10(12): 1236 - 1245.
[Abstract] [Full Text] [PDF]