European Heart Journal Advance Access originally published online on May 4, 2005
European Heart Journal 2005 26(14):1350-1352; doi:10.1093/eurheartj/ehi314
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
Timing of arrhythmic death after myocardial infarction: does it affect timing of ICD implantation?
Cardiologia, Dipartimento di Medicina, Chirurgia e Odontoiatria, Osp. San Paolo, University of Milan, Via A. di Rudinì 8, 201442 Milan, Italy
* Corresponding author. Tel/fax: +39 02 50323145. E-mail address: federico.lombardi@unimi.it
This editorial refers to Temporal trends on the risk of arrhythmic vs. non-arrhythmic deaths in high-risk patients after myocardial infarction: a combined analysis from multicentre trials
by Y.G. Yap et al., on page 1385
| The first 150 words of the full text of this article appear below. |
In spite of significant reduction in total mortality observed in patients discharged after an acute myocardial infarction (MI), ventricular arrhythmias still account for 3040% of deaths. This figure, which was initially provided by studies carried out in the pre-thrombolytic era, has been subsequently confirmed when most of the patients had been revascularized by thrombolysis or percutaneous coronary intervention (PCI).1
Early revascularization and a more generalized use of beta blockers, angiotensin-converting enzyme-inhibitors, statins, and antiplatelet agents have largely contributed to the improvement in the prognosis of patients presenting with an ST-elevated acute MI. Nevertheless, identification of patients at risk remains an issue far from being adequately addressed. There is a general consensus that depressed ventricular function, as reflected by a left ventricular ejection fraction (LVEF) <40%, represents the strongest negative prognostic factor in these patients.1 Different cut-off values have proved effective in recent clinical trials and an LVEF <30% has been
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Related articles in EHJ:
- Temporal trends on the risk of arrhythmic vs. non-arrhythmic deaths in high-risk patients after myocardial infarction: a combined analysis from multicentre trials
- Yee Guan Yap, Trinh Duong, Martin Bland, Marek Malik, Christian Torp-Pedersen, Lars Køber, Stuart J. Connolly, Bradley Marchant, and John Camm
EHJ 2005 26: 1385-1393.[Abstract] [FREE Full Text]