European Heart Journal Advance Access originally published online on May 4, 2005
European Heart Journal 2005 26(14):1446; doi:10.1093/eurheartj/ehi315
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
ASD closure for migraine: is there a scientific basis?
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Mortelmans et al.1 studied the closure of atrial septal defect (ASD) for preventing migraine. These investigators speculate about small right-to-left shunt (RLS) in ASD during Valsalva or exercise,1 blurring the characteristic haemodynamic difference between patent foramen ovale (PFO)RLS and ASDleft-to-right shunt (LRS).2 Additionally, in contrast to PFO with unpredictable
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