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European Heart Journal Advance Access originally published online on June 15, 2005
European Heart Journal 2005 26(18):1813-1815; doi:10.1093/eurheartj/ehi382
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

ST-segment elevation acute myocardial infarction: reperfusion at any cost?

Antonio Abbate1,*, Pierfrancesco Agostoni2 and Giuseppe G.L. Biondi-Zoccai3

1Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, 10025 Bellona Court, Richmond, VA 23233, USA
2Department of Cardiology, AZ Middelheim, Antwerp, Belgium
3Interventional Cardiology Unit, St Raphael University Hospital, Milan, Italy

* Corresponding author. Fax: +1 360 323 1204. E-mail address: abbatea@yahoo.com

This editorial refers to ‘Long-term clinical outcomes after rescue angioplasty are not different from those of successful thrombolysis for acute myocardial infarction’{dagger} by P.G. Steg et al., on page 1831

The first 150 words of the full text of this article appear below.

Acute myocardial infarction (AMI) is defined as an acute ischaemic insult to the myocardium resulting in myocardial necrosis. ST-segment elevation AMI (STEMI) identifies a condition in which the ischaemic insult is the result of an abrupt cessation of coronary flow due to thrombotic occlusion of a relatively large and proximal branch of the coronary circulation. Early, effective, and persistent recanalization of the coronary bed and reperfusion of the myocardium are the goals of the treatment in STEMI.1 Indeed, the earlier the reperfusion the greater the benefits.2 Experimental studies and the results of the early fibrinolytic trials provided useful information on this topic and led to increased awareness among health care providers and general population regarding the concepts of ‘golden hour’ and ‘time is muscle'.2 Thereafter, fibrin-specific agents became available and were shown to be superior to non-specific agents, timely treatment became available in emergency departments throughout the world, and survival . . . [Full Text of this Article]


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Related articles in EHJ:

Long-term clinical outcomes after rescue angioplasty are not different from those of successful thrombolysis for acute myocardial infarction
Philippe Gabriel Steg, Laurent Francois, Bernard Iung, Dominique Himbert, Pierre Aubry, Patrick Charlier, Hakim Benamer, Laurent J. Feldman, and Jean-Michel Juliard
EHJ 2005 26: 1831-1837. [Abstract] [Full Text]