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European Heart Journal Advance Access originally published online on December 17, 2004
European Heart Journal 2005 26(3):207-209; doi:10.1093/eurheartj/ehi078
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European Heart Journal vol. 26 no. 3 © The European Society of Cardiology 2004; all rights reserved.

Broader indications for B-type natriuretic peptide testing in coronary artery disease

Ralph A.H. Stewart*

University of Auckland and Green Lane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Auckland 1030, New Zealand

* Tel: +64 9 630 9903; fax: +64 9 623 6422. E-mail address: rstewart@adhb.govt.nz

This editorial refers to ‘B-type natriuretic peptide: a novel early blood marker of acute myocardial infarction in patients with chest pain and no ST-segment elevation’{dagger} by R. Bassan et al., on page 234 and ‘Analysis of N-terminal-pro-brain natriuretic peptide and C-reactive protein for risk stratification in stable and unstable coronary artery disease: results from the AtheroGene study’{ddagger} by R. Schnabel et al., on page 241

The first 10% of the full text of this article appears below.

B-type natriuretic peptide (BNP) is synthesized by cardiac myocytes when left ventricular wall stress increases. After secretion the pro-hormone is cleaved to the biologically active hormone (BNP) and an inactive N-terminal fragment (N-BNP). There is now reliable evidence that measuring the blood level of either BNP or N-BNP improves the ability to diagnose or exclude heart failure as the cause of acute dyspnoea,1 and provides powerful information on mortality risk both in patients with heart failure and in patients admitted to hospital with an acute coronary syndrome.2 Two papers in this issue of the European Heart Journal suggest that indications for BNP testing could be broadened further to include early diagnosis of myocardial infarction in patients with acute chest pain,3 and to risk . . . [Full Text of this Article]


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Related articles in EHJ:

B-type natriuretic peptide: a novel early blood marker of acute myocardial infarction in patients with chest pain and no ST-segment elevation
Roberto Bassan, Alfredo Potsch, Alan Maisel, Bernardo Tura, Humberto Villacorta, Mônica Viegas Nogueira, Augusta Campos, Roberto Gamarski, Antonio Cláudio Masetto, and Marco Aurélio Moutinho
EHJ 2005 26: 234-240. [Abstract] [FREE Full Text]  

Analysis of N-terminal-pro-brain natriuretic peptide and C-reactive protein for risk stratification in stable and unstable coronary artery disease: results from the AtheroGene study
Renate Schnabel, Hans J. Rupprecht, Karl J. Lackner, Edith Lubos, Christoph Bickel, Jürgen Meyer, Thomas Münzel, François Cambien, Laurence Tiret, Stefan Blankenberg, and for the AtheroGene Investigators
EHJ 2005 26: 241-249. [Abstract] [FREE Full Text]  



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