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European Heart Journal Advance Access originally published online on January 11, 2005
European Heart Journal 2005 26(4):319-321; doi:10.1093/eurheartj/ehi090
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Importance of mitral regurgitation in ischaemic heart disease—more than just a bystander

Luísa M. Branco*

Department of Cardiology, Santa Marta SA Hospital, Rua de Santa Marta, 1169-024 Lisbon, Portugal

* Tel: +351 21 8465469; fax: +351 21 8465469. E-mail address: branco.online@mail.telepac.pt

This editorial refers to ‘Prognostic influence of mitral regurgitation prior to a first myocardial infarction’{dagger} by J. Zamorano et al., on page 343

The first 10% of the full text of this article appears below.

Coronary artery disease (CAD) prognosis has been known for many years to depend on many factors, including the degree of left ventricular (LV) dysfunction as well as the presence of inducible ischaemia, viable dysfunctioning myocardium, and degree of coronary artery lesions. Mitral regurgitation (MR) is often a bystander and is a frequent finding after acute myocardial infarction (AMI) (in 15–64% of patients). It is an independent predictor of cardiovascular mortality,1–4 and results from many factors, such as papillary muscle dysfunction and/or mitral annulus dilatation, and LV remodelling with papillary muscle migration causing malcoaptation of the leaflets and excess valvular tenting with loss of systolic annular contraction.2 Myocardial viability in the infarct area reduces infarct expansion and ventricular remodelling, and prevents the development of MR. In the study by Golia et al.1 of 191 patients after uncomplicated AMI, MR was present in 58.6% of the . . . [Full Text of this Article]


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Related articles in EHJ:

Prognostic influence of mitral regurgitation prior to a first myocardial infarction
José Zamorano, Leopoldo Perez de Isla, Lucía Oliveros, Carlos Almería, José Luis Rodrigo, Adalía Aubele, José Banchs, and Carlos Macaya
EHJ 2005 26: 343-349. [Abstract] [FREE Full Text]