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European Heart Journal Advance Access originally published online on February 4, 2005
European Heart Journal 2005 26(5):426-427; doi:10.1093/eurheartj/ehi141
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Why ventilatory inefficiency matters in chronic heart failure

Andrew J.S. Coats*

University of Sydney, NSW 2006, Australia

* Corresponding author. Tel: +61 235 14579; fax: +61 235 16645. E-mail address: ajscoats@aol.com

This editorial refers to ‘Exercise ventilation inefficiency and cardiovascular mortality in heart failure: the critical independent prognostic value of the arterial CO2 partial pressure’{dagger} by M. Guazzi et al., on page 472

The first 10% of the full text of this article appears below.

Chronic heart failure is a common condition with a poor prognosis. Major treatment advances have been achieved utilizing three main drug classes: the angiotensin-converting enzyme inhibitors (and the similarly acting angiotensin receptor antagonists), beta-blockers, and aldosterone antagonists. Despite our increased knowledge of the pathophysiology of the condition, the generation of symptoms and the causes of exercise intolerance remain confusing. Establishing accurate risk stratification has also proved difficult. While a logical measure such as left ventricular ejection fraction,1 reflecting as it does damage . . . [Full Text of this Article]


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Related articles in EHJ:

Exercise ventilation inefficiency and cardiovascular mortality in heart failure: the critical independent prognostic value of the arterial CO2 partial pressure
Marco Guazzi, Giuseppe Reina, Gabriele Tumminello, and Maurizio D. Guazzi
EHJ 2005 26: 472-480. [Abstract] [FREE Full Text]  



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G. Tumminello, M. Guazzi, P. Lancellotti, and L. A. Pierard
Exercise ventilation inefficiency in heart failure: pathophysiological and clinical significance
Eur. Heart J., March 2, 2007; 28(6): 673 - 678.
[Abstract] [Full Text] [PDF]