European Heart Journal Advance Access originally published online on March 9, 2005
European Heart Journal 2005 26(7):634-636; doi:10.1093/eurheartj/ehi217
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
How should we evaluate an open artery in STEMI patients?
Department of Cardiology, Karolinska University Hospital, Karolinska Institute, S 141 86 Stockholm, Sweden
* Corresponding author. Tel: +46 8 585 817 33; fax: +46 8 585 867 10. E-mail address: stefan.agewall@karolinska.se
This editorial refers to ‘Ageing, impaired myocardial perfusion, and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty’
by G. De Luca et al., on page 662, and ‘Combined prognostic utility of ST-segment recovery and myocardial blush after primary percutaneous coronary intervention in acute myocardial infarction’
by P. Sorajja et al., on page 667
| The first 10% of the full text of this article appears below. |
Acute ST-elevation myocardial infarction (STEMI) is a major cause of mortality and morbidity. After plaque rupture and intracoronary thrombus formation, ischaemia causes damage to myocytes and coronary microcirculation soon after occlusion. In the 1980s, mortality reduction with thrombolytic therapy generated a new standard of care for medical treatment of patients with STEMI. However, fibrinolytic therapy is limited by inadequate epicardial patency, and subsequently it has been shown that mechanical revascularization of the infarct-related coronary artery offers an even greater clinical benefit to patients with STEMI. Thus, the goal of reperfusion treatment in patients with STEMI is to re-establish a patent infarct-related epicardial artery as soon as possible.
The Thrombolysis In Myocardial Infarction (TIMI) group has categorized epicardial coronary flow into four grades (0–3) to
How should an open artery be evaluated in clinical practice?
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Related articles in EHJ:
- Ageing, impaired myocardial perfusion, and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty
- Giuseppe De Luca, Arnoud W.J. van 't Hof, Jan Paul Ottervanger, Jan C.A. Hoorntje, A.T. Marcel Gosselink, Jan-Henk E. Dambrink, Menko-Jan de Boer, and Harry Suryapranata
EHJ 2005 26: 662-666.[Abstract] [Full Text] - Combined prognostic utility of ST-segment recovery and myocardial blush after primary percutaneous coronary intervention in acute myocardial infarction
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EHJ 2005 26: 667-674.[Abstract] [Full Text]
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