European Heart Journal Advance Access originally published online on March 11, 2005
European Heart Journal 2005 26(9):861-862; doi:10.1093/eurheartj/ehi220
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
More hormones spilt in heart failure: linking renal sympathetic activation to clinical outcome
1Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
2Cardiac Catheterization Laboratory, Rigshospitalet, University of Copenhagen, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
* Corresponding author. Tel: +45 3545 5509; fax: +45 3545 4640. E-mail address: jpg@dadlnet.dk
This editorial refers to Long-term outcome in relation to renal sympathetic activity in patients with chronic heart failure
by M. Petersson et al., on page 906
| The first 10% of the full text of this article appears below. |
Neurohumoral activation is a commonly used term in papers dealing with heart failure. Although the term is short, the process is vast and complex: perhaps as complex as it gets. As heart failure affects almost all organs through reduced blood supply and compensatory regulation of auto-, para-, neuro-, and endocrine mechanisms, it seems overwhelming to rank the individual effect and regulation of one bioactive substance to the effects and regulations of others. Which substance affects which system and in what order through the course of disease progression? To make matters more complex, new substances are still being added to the long list of hormones, despite the fact that it has
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EHJ 2005 26: 906-913.[Abstract] [Full Text]