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European Heart Journal Advance Access originally published online on June 7, 2006
European Heart Journal 2006 27(13):1517-1518; doi:10.1093/eurheartj/ehl063
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Myocardial contrast echocardiography: another discriminator of physiological and pathological left ventricular hypertrophy?

Arnoud van der Laarse and Ernst E. van der Wall*

Department of Cardiology, Leiden University Medical Center, PO Box 9600, 2300 Leiden, The Netherlands

* Corresponding author. Tel: +31 71 526 2020; fax: +31 71 526 6809. E-mail address: e.e.van_der_wall@lumc.nl

This editorial refers to ‘The relative myocardial blood volume differentiates between hypertensive heart disease and athlete's heart in humans’{dagger} by A. Indermühle et al., on page 1571

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Left ventricular (LV) hypertrophy is a structural and functional adaption to increased wall stress. For years, there has been an attempt to distinguish physiological hypertrophy, such as occurs in athletes, from pathological hypertrophy, such as occurs in patients with hypertension and hypertrophic cardiomyopathy. Physiological hypertrophy is characterized by normal systolic and diastolic cardiac function and metabolism, and a supranormal coronary vasodilator reserve. Pathological hypertrophy due to pressure overload arises from hypertrophy of myocytes and extravascular collagen deposition, which stiffens the left ventricle, impairs diastolic filling, and leads to reduced coronary vasodilator reserve. In the past, imaging modalities like cardiovascular magnetic resonance and magnetic resonance spectroscopy have assisted in the distinction of physiological vs. pathological hypertrophy.1 A potential . . . [Full Text of this Article]


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Related articles in EHJ:

The relative myocardial blood volume differentiates between hypertensive heart disease and athlete's heart in humans
Andreas Indermühle, Rolf Vogel, Pascal Meier, Simone Wirth, Regula Stoop, Markus G. Mohaupt, and Christian Seiler
EHJ 2006 27: 1571-1578. [Abstract] [Full Text]