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European Heart Journal Advance Access originally published online on June 22, 2006
European Heart Journal 2006 27(14):1644-1645; doi:10.1093/eurheartj/ehi823
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Eisenmenger syndrome: towards identifying the risk factors for death

Narayanswami Sreeram*

Department of Paediatric Cardiology, University Hospital of Cologne, Kerpenerstrasse 62, 50937 Cologne, Germany

* Corresponding author. Tel: +49 221 478 86301; Fax: +49 221 478 86302. E-mail address: n.sreeram@uni-koeln.de

This editorial refers to ‘Presentation, survival prospects and predictors of death in Eisenmenger syndrome: a combined retrospective and case–control study’{dagger} by G.-P. Diller et al., on page 1737

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The first description of Eisenmenger syndrome was provided over a 100 years ago, and the concept of Eisenmenger reaction, with progressive pulmonary vascular disease and reversal of shunt as representing a final pathway for several morphological cardiac defects, is well understood.1 Given the improved awareness of congenital heart disease among paediatricians and cardiologists, the advances in imaging, surgery and intensive care facilities, and that early definitive therapy for the majority of lesions associated with a risk of developing Eisenmenger syndrome is available, a progressive decrease in the prevalence of this disease may be expected. This does not detract from the fact that a significant population of (young) adults is currently under follow-up at various centres throughout the world with this syndrome. Data from several studies suggest that their survival prospects appear to be improving (although . . . [Full Text of this Article]


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Presentation, survival prospects, and predictors of death in Eisenmenger syndrome: a combined retrospective and case–control study
Gerhard-Paul Diller, Konstantinos Dimopoulos, Craig S. Broberg, Mehmet G. Kaya, Utpal Singh Naghotra, Anselm Uebing, Carl Harries, Omer Goktekin, J. Simon R. Gibbs, and Michael A. Gatzoulis
EHJ 2006 27: 1737-1742. [Abstract] [Full Text]  



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G.-P. Diller and M. A. Gatzoulis
Pulmonary Vascular Disease in Adults With Congenital Heart Disease
Circulation, February 27, 2007; 115(8): 1039 - 1050.
[Abstract] [Full Text] [PDF]