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European Heart Journal Advance Access originally published online on July 5, 2006
European Heart Journal 2006 27(15):1764-1766; doi:10.1093/eurheartj/ehi863
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Haemodynamic findings after drug-eluting stenting: expected, provocative, or challenging?

Fernando Alfonso*

Interventional Cardiology, San Carlos University Hospital, Madrid, Spain

* Corresponding author: Cardiología Intervencionista, Instituto Cardiovascular, Hospital Universitario Clínico San Carlos, Plaza de Cristo Rey, Madrid 28040, Spain. Tel: +3491 3303289; fax: +3491 3303289. E-mail address: falf@hotmail.com

This editorial refers to ‘Evaluation of the haemodynamic characteristics of drug-eluting stents at implantation and at follow-up’{dagger} by M. van't Veer et al., on page 1811

The first 150 words of the full text of this article appear below.

In this article van't Veer et al.1 present a comprehensive and detailed study comparing the haemodynamic characteristics of drug-eluting stents (DES) with those obtained by conventional bare metal stents (BMS). After DES, long-term physiological parameters including fractional flow reserve (FFR), hyperaemic gradient, and wall shear stress (WSS) were superior to those found in equivalent BMS implanted in the same patients.1 Although these findings are of major interest, most of the new information provided could be perceived as well expected considering the large body of evidence demonstrating the superb late results after DES implantation. Nevertheless, as will be highlighted in this editorial, some study findings and their potential implications are rather provocative. Furthermore, on the basis of their results, these investigators from the Catharina Hospital (Eindhoven)1 dare to challenge some widely accepted strategies in the management of patients with diffuse coronary artery disease (CAD).

Coronary physiology after DES

Previous land-mark studies from the same . . . [Full Text of this Article]

WSS in atherogenesis and neointimal proliferation

Atherogenesis
Neointimal proliferation
Implications for the management of diffuse CAD


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Related articles in EHJ:

Evaluation of the haemodynamic characteristics of drug-eluting stents at implantation and at follow-up
Marcel van't Veer, Nico H.J. Pijls, Wilbert Aarnoudse, Jacques J. Koolen, and Frans N. van de Vosse
EHJ 2006 27: 1811-1817. [Abstract] [Full Text]