European Heart Journal Advance Access originally published online on September 7, 2006
European Heart Journal 2006 27(19):2260-2262; doi:10.1093/eurheartj/ehl240
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Registries and surveys in acute coronary syndrome
Cardiovascular Research, The University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, UK
* Corresponding author. Tel: +44 131 242 6378; fax: +44 131 242 6379. E-mail address: k.a.a.fox@ed.ac.uk
This editorial refers to ‘The second Euro Heart Survey on acute coronary syndrome: characteristics, treatment and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004’
by L. Mandelzweig et al., on page 2285
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Why do we need registries and surveys?
Randomized controlled trials provide the most secure evidence for the impact of a specific treatment in a defined patient population. However, to study such treatments, the defined patient population often excludes individuals at higher risk, those with co-morbidity, and those with greater risk of complications of the drug or interventional therapy. Hence, unless the trial is very large and heterogeneous, it tends to reflect an ‘ideal’ study set rather than the diversity of clinical practice. Registries conducted in the same centres, and at the same time as clinical trials, have revealed substantially higher co-morbidity and risks of death among those excluded from trials.1 Although it is critically important to define what can be achieved with specific treatments, clinical trials cannot define how such treatments are applied in the diversity of practice. In contrast, registries and surveys, such as the second Euro Heart Survey (EHS II) on ACS,2 have
What can appropriately designed registries and surveys provide?
What has the EHS II added?
Setting standards for registries and surveys
How does the EHS II measure up?
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Related articles in EHJ:
- The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004
- Lori Mandelzweig, Alex Battler, Valentina Boyko, Hector Bueno, Nicolas Danchin, Gerasimos Filippatos, Anselm Gitt, David Hasdai, Yonathan Hasin, Jaume Marrugat, Frans Van de Werf, Lars Wallentin, Shlomo Behar, and on behalf of the Euro Heart Survey Investigators
EHJ 2006 27: 2285-2293.[Abstract] [FREE Full Text]
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