Skip Navigation


European Heart Journal Advance Access originally published online on November 23, 2006
European Heart Journal 2006 27(24):2914-2915; doi:10.1093/eurheartj/ehl373
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
27/24/2914    most recent
ehl373v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in EHJ
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Saunamäki, K. I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Saunamäki, K. I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Virtual histology and the hunt for the vulnerable plaque

Kari I. Saunamäki

Department of Cardiology, The Heart Center, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark

Corresponding author. Tel: +45 35453396; fax: +45 35452705. E-mail address: kari.saunamaki@rh.hosp.dk

This editorial refers to ‘Coronary plaque composition of culprit/target lesions according to the clinical presentation: a virtual histology intravascular ultrasound analysis’{dagger} by J.F. Surmely et al., on page 2939

The first 10% of the full text of this article appears below.

It is a generally accepted concept that acute thrombotic coronary artery occlusion occurs at the site of a vulnerable plaque (VP). Three different types of histopathological entities have been described in coronary arteries from victims of sudden death related to coronary artery disease: (i) plaque rupture, (ii) plaque erosion, and (iii) calcified nodule.1 A ruptured plaque consists of a necrotic core (NC) with ruptured overlying thin fibrous cap. In plaque erosion, there is a luminal thrombus with proteoglycans and smooth muscle cells and minimal inflammation in the vessel wall. NC is absent or covered with a thick fibrous cap. The calcified nodule consists of depot of calcifications with discontinuation of the fibrous cap and the absence of endothelium. In autopsy studies on cases of sudden death, . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in EHJ:

Coronary plaque composition of culprit/target lesions according to the clinical presentation: a virtual histology intravascular ultrasound analysis
Jean-François Surmely, Kenya Nasu, Hiroshi Fujita, Mitsuyasu Terashima, Tetsuo Matsubara, Etsuo Tsuchikane, Mariko Ehara, Yoshihisa Kinoshita, Quan Xiu Zheng, Nobuyoshi Tanaka, Osamu Katoh, and Takahiko Suzuki
EHJ 2006 27: 2939-2944. [Abstract] [FREE Full Text]  



This article has been cited by other articles:


Home page
 Eur Heart JHome page
A. D. Frutkin, S. K. Mehta, J. R. McCrary, and S. P. Marso
Limitations to the use of virtual histology-intravascular ultrasound to detect vulnerable plaque
Eur. Heart J., July 2, 2007; 28(14): 1783 - 1784.
[Full Text] [PDF]