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European Heart Journal Advance Access originally published online on March 29, 2007
European Heart Journal 2007 28(10):1175-1177; doi:10.1093/eurheartj/ehl567
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

False positive or true positive troponin in patients presenting with chest pain but ‘normal’ coronary arteries: lessons from cardiac MRI

Andrew E. Arai

National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg 10, Room B1D416, MSC1061 10 Center Drive, Bethesda, MD 20892-1061, USA

Corresponding author. Tel: +1 301 496 3658; fax: +1 301 402 2389. E-mail address: araia@nih.gov

This editorial refers to ‘The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin and unobstructed coronary arteries’{dagger} by R.G. Assomull et al., on page 1242

The first 10% of the full text of this article appears below.

Cardiac magnetic resonance imaging (MRI), particularly when enhanced with commonly available gadolinium-based contrast agents, is a powerful clinical tool for characterizing myocardial abnormalities. One of the best-known applications of this relatively new technology has been the detection of myocardial infarction. It is also possible to image myocardial scarring or fibrosis in other disease states such as myocarditis and infiltrative cardiomyopathies. Assomull et al.1 from the Royal Brompton Hospital document the adjunctive diagnostic value of late gadolinium enhancement imaging in patients who present with chest pain, elevated troponin but unexpectedly ‘normal’ appearing coronary angiograms.

The introduction of troponin assays revolutionized the diagnosis of acute myocardial infarction. This was largely based on the high sensitivity and specificity for acute myocardial injury. Elevated troponin was associated with adverse prognosis before we came to . . . [Full Text of this Article]


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Related articles in EHJ:

The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries
Ravi G. Assomull, Jonathan C. Lyne, Niall Keenan, Ankur Gulati, Nicholas H. Bunce, Simon W. Davies, Dudley J. Pennell, and Sanjay K. Prasad
EHJ 2007 28: 1242-1249. [Abstract] [FREE Full Text]  



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W P Bandettini and A E Arai
Advances in clinical applications of cardiovascular magnetic resonance imaging
Heart, November 1, 2008; 94(11): 1485 - 1495.
[Abstract] [Full Text] [PDF]