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European Heart Journal Advance Access originally published online on April 25, 2007
European Heart Journal 2007 28(10):1182-1183; doi:10.1093/eurheartj/ehm085
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Importance of left ventricular lead position in cardiac resynchronization therapy

Gabe B. Bleeker*, Martin J. Schalij and Jeroen J. Bax

Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands

* Corresponding author. Tel: +31 71 5262020; fax: +31 71 5266809. E-mail address: g.b.bleeker@lumc.nl

This editorial refers to ‘Impact of left ventricular lead position in cardiac resynchronization therapy on left ventricular remodelling. A circumferential strain analysis based on 2D echocardiography’{dagger} by M. Becker et al., on page 1211

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At present, cardiac resynchronization therapy (CRT) is considered a major breakthrough in the treatment of patients with drug-refractory heart failure. The startling benefits of CRT observed in small initial studies have now been clearly confirmed in large randomized controlled multicentre trials which have now included over 4000 patients.1,2 The beneficial effects of CRT observed in these trials include an improvement in clinical symptoms as well as an improvement in left ventricular (LV) haemodynamics and a reduction in LV volumes. In addition, CRT resulted in a dramatic reduction in heart failure related hospitalizations and a reduction in all-cause mortality. On the . . . [Full Text of this Article]


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Related articles in EHJ:

Impact of left ventricular lead position in cardiac resynchronization therapy on left ventricular remodelling. A circumferential strain analysis based on 2D echocardiography
Michael Becker, Rafael Kramann, Andreas Franke, Ole-A. Breithardt, Nicole Heussen, Christian Knackstedt, Christoph Stellbrink, Patrick Schauerte, Malte Kelm, and Rainer Hoffmann
EHJ 2007 28: 1211-1220. [Abstract] [FREE Full Text]