European Heart Journal Advance Access originally published online on April 30, 2007
European Heart Journal 2007 28(10):1184-1186; doi:10.1093/eurheartj/ehm086
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
CPAP treatment for obstructive sleep apnoea in heart failure: expectations unmet
Division of Pulmonary and Critical Care Medicine (SMC) and Division of Cardiovascular Diseases and Internal Medicine (VKS), Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
* Corresponding author. Tel: +1 507 255 1144; fax: +1 507 255 7070. E-mail address: somers.virend@mayo.edu
This editorial refers to ‘Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo controlled trial’
by L.A. Smith et al., on page 1221
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Heart failure (HF) is an epidemic, increasing in prevalence as the population ages. The Rotterdam Study shows that persons who live to age 55 have a one in three chance of eventually developing HF.1 The staggering prevalence estimate of more than five million currently living with HF in the United States may underestimate the overall problem, since population-based studies find that a substantial proportion of those with systolic dysfunction are asymptomatic, although still at increased mortality risk.2,3 Despite advances in treatment with drugs, lifestyle modifications, and therapeutic devices, mortality from HF continues to rise, fuelling interest in alternative methods of treatment. One such target of therapy has been obstructive sleep apnoea (OSA).
HF and OSA are closely linked by their strong associations with ageing and obesity, and frequently
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Related articles in EHJ:
- Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial
- Lindsay A. Smith, Marjorie Vennelle, Roy S. Gardner, Theresa A. McDonagh, Martin A. Denvir, Neil J. Douglas, and David E. Newby
EHJ 2007 28: 1221-1227.[Abstract] [FREE Full Text]
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  V. K. Somers, D. P. White, R. Amin, W. T. Abraham, F. Costa, A. Culebras, S. Daniels, J. S. Floras, C. E. Hunt, L. J. Olson, et al. Sleep Apnea and Cardiovascular Disease: An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing In Collaboration With the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health) Circulation, September 2, 2008; 118(10): 1080 - 1111. [Full Text] [PDF]
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 J. M. Golbin, V. K. Somers, and S. M. Caples Obstructive Sleep Apnea, Cardiovascular Disease, and Pulmonary Hypertension Proceedings of the ATS, February 15, 2008; 5(2): 200 - 206. [Abstract] [Full Text] [PDF]
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