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European Heart Journal Advance Access originally published online on May 9, 2007
European Heart Journal 2007 28(11):1279-1280; doi:10.1093/eurheartj/ehm111
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Myocarditis and heart failure: need for better diagnostic, predictive, and therapeutic tools

Stephane Heymans

Experimental and Molecular Cardiology/CARIM, Department of Cardiology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands

Corresponding author. Tel: +31 43 3882949; fax: +31 43 3871055. E-mail address: s.heymans@cardio.unimaas.nl

This editorial refers to ‘A prospective study of biopsy-proven myocarditis: prognostic relevance of clinical and aetiopathogenetic features at diagnosis’{dagger} by A.L.P. Caforio et al., on page 1326

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Viral infection of the heart is increasingly recognized as an important cause of both acute and chronic heart failure. Enteroviruses and adenoviruses have been considered the most common pathogens of viral cardiomyopathy (CMP), but parvovirus B19 (PVB19) is increasingly found in endomyocardial biopsies of patients with acute myocarditis or idiopathic dilated cardiomyopathy (ICM).1,2 In addition to direct cytopathic effects of these cardiotropic viruses, there is convincing evidence that autoimmune responses induced by viruses contribute to the heart disease in a significant subset of patients with myocarditis.3

Caforio et al.4 present a prospective study in 174 consecutive patients with myocarditis included between 1992 and 2005. . . . [Full Text of this Article]


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Related articles in EHJ:

A prospective study of biopsy-proven myocarditis: prognostic relevance of clinical and aetiopathogenetic features at diagnosis
Alida L.P. Caforio, Fiorella Calabrese, Annalisa Angelini, Francesco Tona, Annalisa Vinci, Stefania Bottaro, Angelo Ramondo, Elisa Carturan, Sabino Iliceto, Gaetano Thiene, and Luciano Daliento
EHJ 2007 28: 1326-1333. [Abstract] [FREE Full Text]  



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R. Dennert, H. J. Crijns, and S. Heymans
Acute viral myocarditis
Eur. Heart J., September 1, 2008; 29(17): 2073 - 2082.
[Abstract] [Full Text] [PDF]