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European Heart Journal Advance Access originally published online on May 24, 2007
European Heart Journal 2007 28(13):1539-1540; doi:10.1093/eurheartj/ehm167
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Is the chest pain in cardiac syndrome X due to subendocardial ischaemia?

Paolo G. Camici

MRC Clinical Sciences Centre and National Heart and Lung Institute, Imperial College, Hammersmith Campus, Du Cane Road, London W12 0NN, UK

Corresponding author. Tel: +44 20 8383 3186; fax: +44 20 8383 3742. E-mail address: paolo.camici@csc.mrc.ac.uk

This editorial refers to ‘Is subendocardial ischaemia present in patients with chest pain and normal coronary angiograms? A cardiovascular MR study’ by I.A.C. Vermeltfoort et al., on page 1554

The first 10% of the full text of this article appears below.

Over the past 30 years, the issue of chest pain in patients with a normal coronary angiogram has received much attention.1 The interest in this condition, which has also been termed cardiac syndrome X when the pain is accompanied by ST-segment depression during exercise electrocardiography, has two main reasons:

(i) The first is clinical. Does the patient have heart disease? Can the condition be effectively treated? Is the patient's life expectancy shortened? (ii) The second one is relative to the pathophysiology of this condition. Is the chest pain in patients with syndrome X of ischaemic origin? And if the pain is due to myocardial ischaemia what are the mechanisms?

Clinically, in a significant proportion of patients with a history of chest pain, the coronary angiogram does not show significant narrowing of the vessel lumen. These patients usually have a poor response to . . . [Full Text of this Article]


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Related articles in EHJ:

Is subendocardial ischaemia present in patients with chest pain and normal coronary angiograms? A cardiovascular MR study
Ilse A.C. Vermeltfoort, Olga Bondarenko, Pieter G.H.M. Raijmakers, Diego A.M. Odekerken, Aaf F.M. Kuijper, Anton Zwijnenburg, Mary J.E. van der Vis-Melsen, Jos W.R. Twisk, Aernout M. Beek, Gerrit J.J. Teule, and Albert C. van Rossum
EHJ 2007 28: 1554-1558. [Abstract] [FREE Full Text]  



This article has been cited by other articles:


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R. O. Cannon III
Microvascular angina and the continuing dilemma of chest pain with normal coronary angiograms.
J. Am. Coll. Cardiol., September 1, 2009; 54(10): 877 - 885.
[Abstract] [Full Text] [PDF]