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European Heart Journal Advance Access originally published online on June 26, 2007
European Heart Journal 2007 28(15):1793-1794; doi:10.1093/eurheartj/ehm261
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Deciphering the mystery of the leaky pulmonary valve in a new era of interventional cardiology

Luc Mertens*

Pediatric Cardiology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium

* Corresponding author. Tel: +32 16 343865; fax: +32 16 343981. E-mail address: luc.mertens@uzleuven.be

This editorial refers to ‘Physiological consequences of percutaneous pulmonary valve implantation: the different behaviour of volume- and pressure-overloaded ventricles’ by L. Coats et al., on page 1886

LM is a Clinical Researcher for the Fund for Scientific Research (FWO), Belgium.

The first 10% of the full text of this article appears below.

Deciphering the effect of pulmonary regurgitation on right ventricular (RV) function in patients after tetralogy of Fallot correction and deciding on timing for valve replacement seems like cracking the Da Vinci code. This question has become the Holy Grail of congenital cardiology in the 21st century. Every piece of information bringing us closer to an answer based on sound scientific data therefore is of great importance. The study by Coats et al.,1 looking at the haemodynamic effect of percutaneous pulmonary valve implantation (PPVI) in patients with predominantly pulmonary regurgitation and RV volume overload, provides new insight into the physiological consequences of relieving chronic pulmonary regurgitation. The great advantage of this unique model is that it avoids the confounding effects of cardiopulmonary bypass and cardiac surgery. When prospectively studying their patients . . . [Full Text of this Article]


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Related articles in EHJ:

Physiological consequences of percutaneous pulmonary valve implantation: the different behaviour of volume- and pressure-overloaded ventricles
Louise Coats, Sachin Khambadkone, Graham Derrick, Marina Hughes, Rod Jones, Bryan Mist, Denis Pellerin, Jan Marek, John E. Deanfield, Philipp Bonhoeffer, and Andrew M. Taylor
EHJ 2007 28: 1886-1893. [Abstract] [Full Text]