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European Heart Journal Advance Access originally published online on September 28, 2007
European Heart Journal 2007 28(21):2563-2564; doi:10.1093/eurheartj/ehm434
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

The apoB/apoA-I ratio and insulin resistance: sorting out the metabolic syndrome

Allan D. Sniderman

Mike Rosenbloom Laboratory for Cardiovascular Research, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Avenue West Montreal, Quebec H3A 1A1, Canada

Corresponding author. Tel: +1 514-934-1934 ext. 34637; fax: +1 514-843-2843. E- mail address: allansniderman@hotmail.com

This editorial refers to ‘ApoB/apoA-I ratio: an independent predictor of insulin resistance in US non-diabetic subjects’ by J. Sierra-Johnson et al., on page 2637

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

Sierra-Johnson et al.1 demonstrate that the apoB/apoA-I ratio is an independent predictor of insulin resistance in non-diabetic Americans. This was the case in men and women and was independent of the traditional risk factors, components of the metabolic syndrome, and inflammatory risk markers such as C-reactive protein (CRP). The strengths of this study are the meticulous construction of the NHANES database on which it is based and the meticulous analysis of it that was undertaken. Previously, these authors and others have shown that the apoB/apoA-I ratio becomes progressively more abnormal as the number of components . . . [Full Text of this Article]


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Related articles in EHJ:

ApoB/apoA-I ratio: an independent predictor of insulin resistance in US non-diabetic subjects
Justo Sierra-Johnson, Abel Romero-Corral, Virend K. Somers, Francisco Lopez-Jimenez, Göran Walldius, Anders Hamsten, Mai-Lis Hellénius, and Rachel M. Fisher
EHJ 2007 28: 2637-2643. [Abstract] [FREE Full Text]  



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J. Sierra-Johnson, R. M. Fisher, A. Romero-Corral, V. K. Somers, F. Lopez-Jimenez, J. Ohrvik, G. Walldius, M.-L. Hellenius, and A. Hamsten
Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population
Eur. Heart J., March 2, 2009; 30(6): 710 - 717.
[Abstract] [Full Text] [PDF]