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European Heart Journal Advance Access originally published online on November 5, 2007
European Heart Journal 2007 28(24):2960-2961; doi:10.1093/eurheartj/ehl399
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© The European Society of Cardiology 2007. All rights reserved. For permissions please email: journals.permissions@oxfordjournals.org

When renal and cardiac insufficiencies intersect: is there a role for natriuretic peptide testing in the ‘cardio-renal syndrome’?

Roland R.J. van Kimmenade1, Yigal Pinto1 and James L. Januzzi, Jr2,*

1 Department of Cardiology, University Hospital Maastricht, The Netherlands
2 Division of Cardiology, Massachusetts General Hospital, Yawkey 5800, 55 Fruit Street, Boston, MA 02114, USA

* Corresponding author. Tel: +1 617 726 3443; fax: +1 617 643 1620. E-mail address: jjanuzzi@partners.org

Footnotes

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology. Back

The first 10% of the full text of this article appears below.

This editorial refers to ‘Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure’ by R.S. Gardner et al., on page 3027

Gardner et al.,1 report that NT-proBNP maintains strong prognosis in heart failure (HF) patients with renal impairment. This is an interesting contribution to the debate about the utility of NT-proBNP in renal impairment; chronic kidney disease is an important complication in patients suffering from HF, while there is often heated discussion about the usefulness of BNP and NT-proBNP measurement in patients with renal insufficiency.

Because of considerable overlap of risk factors and a myriad of pathophysiologic mechanisms, insufficiencies of the renal and cardiac system are tightly related.2 Furthermore, when . . . [Full Text of this Article]


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Related articles in EHJ:

Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure
Roy S. Gardner, Kwok S. Chong, Eileen O’Meara, Alan Jardine, Ian Ford, and Theresa A. McDonagh
EHJ 2007 28: 3027-3033. [Abstract] [Full Text]