Skip Navigation


European Heart Journal Advance Access originally published online on March 5, 2007
European Heart Journal 2007 28(6):661-663; doi:10.1093/eurheartj/ehm008
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
28/6/661    most recent
ehm008v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in EHJ
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bayes-Genis, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bayes-Genis, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Hypertrophy and inflammation: too much for one heart

Antoni Bayes-Genis*

Departament de Medicina, Cardiac Regeneration Program, Cardiology Service, Hospital de la Santa Creu i Sant Pau, Institut Català de Ciencies Cardiovasculars, Universitat Autònoma de Barcelona, Barcelona, Spain

* Corresponding author. Tel: +34 93 2919258; fax: +34 93 5565603. E-mail address: abayesgenis@santpau.es

This editorial refers to ‘Myocarditis in hypertrophic cardiomyopathy patients presenting acute clinical deterioration’{dagger} by A. Frustaci et al., on page 733

The first 10% of the full text of this article appears below.

Hypertrophic cardiomyopathy (HCM) is a genetically determined disease characterized by heterogeneous genetic, morphologic, and clinical patterns. Although it is half a century since Teare1 first described the disease, interest in HCM is growing as we move from understanding disease pathology towards prognostic assessment and risk stratification.

Microscopic findings of HCM are distinctive and include myocardial hypertrophy and gross disorganization of cardiac fibres. Cellular disarray and disorganization of the myofibrillar architecture within a given cell are standard.2 Patients with HCM often exhibit myocyte necrosis and replacement fibrosis in the left ventricle. A spectrum of severity and distribution is observed, ranging from isolated small scars to extensive transmural fibrosis. These pathological features are considered the consequence of myocardial ischaemia due to coronary microvascular . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in EHJ:

Myocarditis in hypertrophic cardiomyopathy patients presenting acute clinical deterioration
Andrea Frustaci, Romina Verardo, Marina Caldarulo, Maria Cristina Acconcia, Matteo A. Russo, and Cristina Chimenti
EHJ 2007 28: 733-740. [Abstract] [FREE Full Text]