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European Heart Journal Advance Access originally published online on March 19, 2007
European Heart Journal 2007 28(7):782-784; doi:10.1093/eurheartj/ehm014
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Renal function, revascularization and risk

Graham S. Hillis1,*, Brian H. Cuthbertson2 and Bernard L. Croal3

1 Department of Cardiology, Aberdeen Royal Infirmary
2 Health Services Research Unit, University of Aberdeen
3 Department of Clinical Biochemistry, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK

* Corresponding author. Tel: +44 1224 558810; fax: +44 1224 554329. E-mail address: g.hillis@abdn.ac.uk

This editorial refers to ‘Renal insufficiency and long-term mortality and incidence of myocardial infarction in patients undergoing coronary artery bypass grafting’{dagger} by M.J. Holzmann et al., on page 865

The first 10% of the full text of this article appears below.

In 1974, 14 years after the advent of regular maintenance haemodialysis, Linder et al.1 first reported the powerful relationship between end-stage renal failure and cardiovascular complications. This is now generally recognized, and the statistics quantifying this excess risk, such as the 100-fold increase in cardiovascular mortality associated with a requirement for chronic dialysis below the age of 45 years, are frequently quoted. More recently, however, clinicians have become aware of the association between milder degrees of renal dysfunction and cardiac morbidity and mortality.

There are several reasons for an increased interest in the relationship between kidney and cardiovascular disease. An ageing population with a greater prevalence of obesity, hypertension, and diabetes has resulted in rising levels of chronic renal disease. Among 6233 participants in the Framingham Heart Study, 8% had mild renal insufficiency based on measures of serum creatinine.2 Likewise, the third National Health . . . [Full Text of this Article]

Renal dysfunction in patients undergoing myocardial revascularization

Relationship between estimated GFR and outcome

Mechanisms whereby pre-procedural renal function influences outcome

Effects of post-procedural renal function on outcome

Clinical implications


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Related articles in EHJ:

Renal insufficiency and long-term mortality and incidence of myocardial infarction in patients undergoing coronary artery bypass grafting
Martin J. Holzmann, Niklas Hammar, Staffan Ahnve, Tobias Nordqvist, Kenneth Pehrsson, and Torbjörn Ivert
EHJ 2007 28: 865-871. [Abstract] [Full Text]