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European Heart Journal Advance Access originally published online on April 12, 2007
European Heart Journal 2007 28(8):924-925; doi:10.1093/eurheartj/ehm079
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Left ventricular dyssynchrony and functional mitral regurgitation: two dynamic conditions

Luc A. Piérard*

Department of Cardiology, University Hospital Sart Tilman, B-4000 Liege, Belgium

* Tel: +32 4 366 71 94; fax: +32 4 366 71 95. E-mail address: lpierard@chu.ulg.ac.be

This editorial refers to ‘Effect of dynamic myocardial dyssynchrony on mitral regurgitation during supine bicycle exercise stress echocardiography in patients with idiopathic dilated cardiomyopathy and "narrow" QRS’{dagger} by A. D'Andrea et al., on page 1004

The first 10% of the full text of this article appears below.

A 30-year-old-man was admitted to the hospital in NYHA class IV without any medical treatment. The coronary arteries were normal. Left ventricular (LV) ejection fraction (EF) was 30%, mean capillary wedge pressure was 38 mmHg. The QRS duration was 120 ms. Myocardial biopsy revealed signs of idiopathic cardiomyopathy without inflammatory infiltration. The patient was treated by lisinopril, carvedilol, and spironolactone and progressively improved. One month later, a Doppler echocardiogram revealed important LV dilatation and reduced EF of 21%. Severe mitral regurgitation (MR) was observed: the effective regurgitant orifice (ERO) was 30 mm2. Significant LV dyssynchrony was found: the difference between time to peak systolic velocities of septal and lateral segments . . . [Full Text of this Article]


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Related articles in EHJ:

Effect of dynamic myocardial dyssynchrony on mitral regurgitation during supine bicycle exercise stress echocardiography in patients with idiopathic dilated cardiomyopathy and ‘narrow’ QRS
Antonello D'Andrea, Pio Caso, Sergio Cuomo, Raffaella Scarafile, Gemma Salerno, Giuseppe Limongelli, Giovanni Di Salvo, Sergio Severino, Luigi Ascione, Paolo Calabrò, Massimo Romano, Gianpaolo Romano, Lucio Santangelo, Ciro Maiello, Maurizio Cotrufo, and Raffaele Calabrò
EHJ 2007 28: 1004-1011. [Abstract] [FREE Full Text]  



This article has been cited by other articles:


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A. D'Andrea and R. Calabro
Effect of dynamic myocardial dyssynchrony on mitral regurgitation during supine bicycle exercise stress echocardiography in patients with idiopathic dilated cardiomyopathy and 'narrow 'QRS: reply
Eur. Heart J., October 2, 2007; 28(20): 2554 - 2555.
[Full Text] [PDF]

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L. A. Pierard and P. Lancellotti
When and how does cardiac resynchronization therapy reduce dynamic mitral regurgitation?
Eur. Heart J., September 1, 2007; 28(17): 2055 - 2056.
[Full Text] [PDF]